Hydroxycoumarins: New, effective plant-derived compounds reduce Ralstonia pseudosolanacearum populations and control tobacco bacterial wilt

Microbiological Research
Liang YangWei Ding

Abstract

Plant wilt disease caused by the soilborne bacterial pathogen Ralstonia pseudosolanacearum is one of the most devastating plant diseases; however, no effective protection against this disease has been developed. Coumarins are important natural plant-derived compounds with a wide range of bioactivities and extensive applications in medicine and agriculture. In the present study, three hydroxycoumarins (Hycs), umbelliferone (UM), esculetin (ES) and daphnetin (DA) significantly inhibited the growth of R. pseudosolanacearum on solid medium in a concentration-dependent manner, and the minimum inhibitory concentration (MICs) of these compounds was 325  mg L-1, 125 mg L-1 and 75 mg L-1, respectively. The percentage of live cells of R. pseudosolanacearum when supplemented with UM, ES, and DA was 63.61%, 17.81% and 7.23%, respectively, which were significantly lower than the DMSO treatment with 92%. Furthermore, irrigating roots with hydroxycoumarins (Hycs) 24 h before inoculation with R. pseudosolanacearum significantly delayed the occurrence of tobacco bacterial wilt, with the control efficiency of the DA treatment (the most efficient of Hycs treatment) 80.03%, 69.83%, 59.19%, 45.49%, 44.12%, 38.27% at 6, 8, 10, 12, 14, and 16 days af...Continue Reading

Citations

Jan 19, 2019·Chemistry & Biodiversity·Thalía I Ramírez-ReyesJosé A Guerrero-Analco
Aug 17, 2019·International Journal of Molecular Sciences·Dylan R ZeissIan A Dubery
May 8, 2020·Oxidative Medicine and Cellular Longevity·Emad H M HassaneinAyman M Mahmoud
Jun 19, 2020·International Journal of Environmental Research and Public Health·Pramod Kumar SahuAnil Kumar Saxena
Oct 23, 2020·Microbes and Environments·Hui-Zhen FuMasafumi Shimizu
Feb 23, 2021·Frontiers in Microbiology·Dehong ZhengQiqin Li
Nov 23, 2021·Phytotherapy Research : PTR·Linlin ZhangXiaofang Li

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