Hydroxylation and oxidation of nalidixic acid in the turtle Pseudemys scripta elegans

The Veterinary Quarterly
T B VreeY A Hekster

Abstract

The turtle Pseudemys scripta elegans hydroxylates nalidixic acid into 7-hydroxynalidixic acid; this latter metabolite is oxidised into 7-carboxynalidixic acid. The elimination half-life of nalidixic acid in the turtle is 30 h. No glucuronides of nalidixic- and 7-hydroxynalidixic acid are formed, as they are in man.

References

Mar 1, 1987·Zentralblatt für Veterinärmedizin. Reihe A·T B VreeJ F Nouws
Oct 14, 1988·Pharmaceutisch Weekblad. Scientific Edition·T B VreeY A Hekster
Sep 1, 1986·Journal of Veterinary Pharmacology and Therapeutics·T B VreeJ F Nouws
May 1, 1981·Clinical Pharmacology and Therapeutics·N FerryJ Sassard
May 1, 1964·Toxicology and Applied Pharmacology·E W MCCHESNEYD ROSI

Citations

Feb 1, 1994·Journal of Veterinary Pharmacology and Therapeutics·T B VreeJ F Nouws
Sep 30, 2000·The International Journal of Neuroscience·A BieleckiP Holas
Feb 18, 2016·Cyberpsychology, Behavior and Social Networking·Brenda K WiederholdJosé Gutiérrez-Maldonado
Aug 30, 2003·Psychophysiology·Mika Koivisto, Antti Revonsuo
Feb 1, 1994·Journal of Veterinary Pharmacology and Therapeutics·T B VreeJ F Nouws
Jan 1, 1989·The Veterinary Quarterly·T B VreeJ C Hafkenscheid
Apr 28, 2005·Psychological Research·Michael F Bunting, Nelson Cowan

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