PMID: 1166074Sep 11, 1975

Hydroxyurea-induced erythroid differentiation

Proceedings of the Society for Experimental Biology and Medicine
N J RencriccaF Stohlman


Hydroxyurea, a cytotoxic agent which destroys cells in DNA synthesis, has been shown to evoke the differentiation of a small number of hemopoietic precursor cells in the erythroid series of erythropoietically suppressed hypertransfused mice. This effect does not appear to be mediated by erythropoietin (EP) since the simultaneous injection of anti-EP did not alter this response.


Aug 1, 1984·The Journal of Clinical Investigation·O S PlattD G Nathan
Jun 1, 1985·The Journal of Clinical Investigation·N L LetvinD G Nathan
Jan 1, 1985·Annals of the New York Academy of Sciences·D G Nathan
Mar 1, 1978·Cell and Tissue Kinetics·E NecasJ Neuwirt

Related Concepts

Cell Density
Hematocrit Procedure
Colony-Forming Units, Hematopoietic

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