Hydroxyurea makes inflammation "just right"?

Blood
Lewis L Hsu

Abstract

Hydroxyurea treatment of sickle cell mice improved their survival from pneumococcal pneumonia, counteracting the abnormally elevated inflammatory response and reducing invasion of bacteria into the bloodstream, through down regulation of E-selectin.

References

Dec 20, 2003·American Journal of Respiratory and Critical Care Medicine·J David HoltzclawLewis L Hsu
Feb 12, 2009·Hemoglobin·Nicola ConranFernando F Costa

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