Hydrozoan nematocytes send and receive synaptic signals induced by mechano-chemical stimuli

The Journal of Experimental Biology
Dominik OliverU Thurm

Abstract

Nematocytes, the stinging cells of Hydrozoa, can be considered as prototypic mechanosensory hair cells bearing a concentric hair bundle, the cnidocil apparatus. These cells produce typical mechanoreceptor potentials in response to deflection of their cnidocil. Here we show that mechanosensory signals are relayed to neighbouring nematocytes via chemical neurotransmission and that nematocytes receive synaptic input from surrounding nematocytes, hair cells and probably from epithelial cells. Intracellular voltage recordings from stenotele nematocytes of capitate hydroid polyps showed two distinct types of responses when other nematocytes within the same tentacle were mechanically stimulated: (i) graded depolarizations of variable duration ('L-potentials'), and (ii) uniform impulse-like, often repetitive depolarizations ('T-potentials') that occurred in correlation with contractions of epitheliomuscular cells. Voltage clamp experiments showed that despite the stereotyped time course of T-potentials, their generation did not involve electrically excitable conductances. Instead, time course, post-stimulus delay, susceptibility to blockers of neurotransmission and gap junctions, and induction by electrical stimulation of other nematoc...Continue Reading

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Mar 22, 2013·Invertebrate Neuroscience : in·T D Mayorova, I A Kosevich
Jun 15, 2010·Neuroscience and Biobehavioral Reviews·David J Albert
Dec 31, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Luis Alberto Bezares-CalderónGáspár Jékely
May 28, 2016·Neuromolecular Medicine·Ronald S PetraliaPamela J Yao
May 27, 2020·ELife·Keiko WeirNicholas W Bellono
Sep 17, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery

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