Hyper-priming in cannabis users: a naturalistic study of the effects of cannabis on semantic memory function

Psychiatry Research
Celia J A MorganH Valerie Curran

Abstract

Psychotic symptoms have theoretically been linked to semantic memory impairments in patients with schizophrenia. Little is known of the effects of cannabis, the world's most popular illicit drug, on semantic memory and whether they are linked to the psychotomimetic states elicited by the drug. Thirty-six cannabis users were tested whilst under the influence of cannabis. They were then tested again when not intoxicated and compared with 38 non-drug using controls. Semantic memory was assessed using a semantic priming task with a long and short stimulus onset asynchrony (SOA) to differentiate automatic and controlled processing. Under the influence of cannabis, users showed increases in both automatic semantic priming and schizotypal symptoms compared with controls. When abstinent, cannabis users exhibited hyper-priming at long SOAs. Cannabis users did not differ from controls in either trait schizotypy or state schizotypy when not intoxicated. Acute cannabis use increases schizotypyal symptoms and may increase automatic semantic priming in recreational users of this drug. When drug-free, cannabis users did not differ from controls in schizotypy but did show hyper-priming at the long SOA. The acute increase in automatic semantic ...Continue Reading

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Citations

Jan 25, 2013·Behavior Research Methods·Keith A HutchisonErin Buchanan
Feb 10, 2016·Biological Psychiatry·Samantha J BroydNadia Solowij
Jul 19, 2013·Cognitive Neuropsychiatry·Erica NeillMariah Kordzadze
Sep 22, 2012·Human Psychopharmacology·Stefania BattistellaH Valerie Curran
Jan 11, 2012·Consciousness and Cognition·Gráinne SchaferH Valerie Curran
Feb 15, 2020·Neuroscience and Biobehavioral Reviews·Y DanijuP Allen
Feb 16, 2021·Neuroscience and Biobehavioral Reviews·Lilian KloftHenry Otgaar
Aug 24, 2021·Frontiers in Behavioral Neuroscience·Christina IoannidouGiovanni Marsicano

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