Hyperbaric oxygen as an adjunctive therapy for bilateral compartment syndrome, rhabdomyolysis and acute renal failure after heroin intake

Archives of Medical Research
Mahdi S AbdullahNawras K Baban

Abstract

Heroin abuse causes various medical and surgical complications. We report a case of heroin-induced severe bilateral compartment syndrome complicated by rhabdomyolysis, acute renal failure and extremely elevated creatinine kinase. A 30-year-old male heroin addict presented to the emergency department of Mount Vernon Hospital, Mount Vernon, New York complaining of severe pain and burning sensation in both legs and feet 1 day after abusing intravenous heroin. He had severe swelling and tenderness of both legs and feet. Laboratory data revealed tremendous elevation of creatine kinase (236,000 IU/L) consistent with rhabdomyolysis. Acute renal failure developed over subsequent days. Treatment consisted of fasciotomy, hyperbaric oxygen therapy (HBO2) and supportive therapy. The condition gradually improved over 4 weeks and the patient did not require dialysis or amputation.

References

Jan 1, 1991·Annales Françaises D'anesthèsie Et De Rèanimation·B ZerrJ Fogliani
Jul 1, 1991·The Australian and New Zealand Journal of Surgery·M J Vucak
Jun 1, 1990·The American Journal of Forensic Medicine and Pathology·Y F ChanT C Chow
Aug 20, 1973·JAMA : the Journal of the American Medical Association·Y B ChallenorJ Pearson
Sep 1, 1967·Clinica Chimica Acta; International Journal of Clinical Chemistry·P KoskeloO Wager
Dec 1, 1994·Annals of Emergency Medicine·W L PrynnC V Pollack
Jan 1, 1995·Journal of Toxicology. Clinical Toxicology·C C YangJ F Deng
Jan 1, 1997·Neurology·T KlockgetherJ Dichgans
Aug 5, 1999·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·L FunkH de Silva
Jun 23, 2000·The Journal of Emergency Medicine·J R Richards
Jan 5, 2001·Clinical Nephrology·E K RiceL P McMahon
Apr 25, 2002·Emergency Medicine Journal : EMJ·B McCannJ McCann

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Citations

Oct 24, 2007·Peptides·Richard J Bodnar
Jul 25, 2006·Medical Hypotheses·Noori S Al-Waili, Glenn J Butler
Sep 9, 2009·Current Problems in Surgery·Christopher J DenteDavid V Feliciano
Dec 31, 2017·BMC Nephrology·Kanaan MansoorZeid J Khitan
Aug 16, 2013·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Varun Parkash SinghAmteshwar Singh Jaggi
Jul 26, 2011·The International Journal of Artificial Organs·George KosmadakisSpiridon Michail
Nov 13, 2020·Journal of Orthopaedic Trauma·Sharri J MortensenArvind G von Keudell

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