Hyperbaric oxygen therapy in femoral head necrosis

The Journal of Arthroplasty
Enrico M CamporesiThomas L Bernasek

Abstract

We evaluated hyperbaric oxygen (HBO) therapy on a cohort of patients with femoral head necrosis (FHN). This double-blind, randomized, controlled, prospective study included 20 patients with unilateral FHN. All were Ficat stage II, treated with either compressed oxygen (HBO) or compressed air (HBA). Each patient received 30 treatments of HBO or HBA for 6 weeks. Range of motion, stabilometry, and pain were assessed at the beginning of the study and after 10, 20, and 30 treatments by a blinded physician. After the initial 6-week treatment, the blind was broken; and all HBA patients were offered HBO treatment. At this point, the study becomes observational. Pretreatment, 12-month. and 7 year-follow-up magnetic resonance images were obtained. Statistical comparisons were obtained with nonparametric Mann-Whitney U test. Significant pain improvement for HBO was demonstrated after 20 treatments. Range of motion improved significantly during HBO for all parameters between 20 and 30 treatments. All patients remain substantially pain-free 7 years later: none required hip arthroplasty. Substantial radiographic healing of the osteonecrosis was observed in 7 of 9 hips. Hyperbaric oxygen therapy appears to be a viable treatment modality in pa...Continue Reading

References

May 28, 1992·The New England Journal of Medicine·H J Mankin

❮ Previous
Next ❯

Citations

Jul 31, 2014·Current Rheumatology Reports·T Andrew EhmkeMichael A Mont
Jan 17, 2015·Indian Journal of Orthopaedics·Sujit Kumar TripathyRamesh Kumar Sen
Jul 16, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Mark D MurpheyMark J Kransdorf
Mar 12, 2015·Orthopedics·Lior KorenEli Peled
Apr 8, 2017·Journal of Enzyme Inhibition and Medicinal Chemistry·Giuliano VezzaniGerardo Bosco
Feb 20, 2017·Advanced Drug Delivery Reviews·Huaifa Zhang, Jake E Barralet
Jun 6, 2018·Clinical Trials : Journal of the Society for Clinical Trials·C A Lansdorp, Rob A van Hulst
Oct 1, 2017·The Bone & Joint Journal·M ChughtaiM A Mont
Jan 10, 2018·International Wound Journal·Frances R HenshawFreya MacMillan
Oct 3, 2018·Journal of Enzyme Inhibition and Medicinal Chemistry·Gerardo BoscoEnrico Camporesi
Nov 2, 2012·The Open Orthopaedics Journal·K L Chan, C C Mok
Dec 17, 2015·Archives of Orthopaedic and Trauma Surgery·A RothS J Breusch
Aug 15, 2014·Experimental and Therapeutic Medicine·Cheng WangShibi Lu
Nov 6, 2013·The Bone & Joint Journal·K IssaM A Mont
Apr 12, 2016·Oral Diseases·P CeponisJ J Freiberger
Jul 26, 2011·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Asim RajpuraTimothy N Board
Apr 18, 2019·EFORT Open Reviews·Daniel PetekDomizio Suva
Feb 18, 2020·Medical Hypotheses·Tanja BatinacIgor Barković
Oct 9, 2015·The Journal of Bone and Joint Surgery. American Volume·Michael A MontJay R Lieberman
Jan 4, 2021·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Wataru AndoNobuhiko Sugano
Jul 13, 2020·Morphologie : Bulletin De L'Association Des Anatomistes·P Massin
Jul 13, 2020·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Merav BarPaul A Carpenter
Apr 4, 2021·International Journal of Environmental Research and Public Health·Emma PadernoGerardo Bosco
Oct 8, 2013·The Orthopedic Clinics of North America·Samik BanerjeeMichael A Mont
Apr 13, 2021·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Ibrahim BozkurtEsra Artvinli Akgul

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
David Weldon
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Xudong LiGary Balian
© 2021 Meta ULC. All rights reserved