Hypercholesterolemia Is Associated with the Subjective Evaluation of Postoperative Outcomes in Patients with Idiopathic Carpal Tunnel Syndrome Who Undergo Surgery: A Multivariate Analysis

Plastic and Reconstructive Surgery
Koichi YanoTakeshi Egi

Abstract

Carpal tunnel syndrome is a compression neuropathy of the median nerve at the wrist; its symptoms include neuropathic pain and sensory and motor disturbance distributed by the median nerve. Carpal tunnel syndrome and hypercholesterolemia have similar backgrounds, but the effect of these similarities on postoperative outcomes has not been reported. Using multivariate analysis, the authors analyzed the relationship between prognostic factors, including the presence of hypercholesterolemia, and subjective postoperative outcomes of patients with idiopathic carpal tunnel syndrome. Of 168 hands with carpal tunnel syndrome that were treated surgically, 141 that were followed up and assessed 1 year postoperatively or thereafter were included. The mean postoperative follow-up period was 40.8 months. Surgery was performed through a small palmar skin incision under local anesthesia. The outcomes were postoperative symptoms, including pain and numbness, and overall Kelly assessment. Preoperative numbness and pain resolved and alleviated in 94 of 141 hands and was diminished in 59 of 64 hands. Univariate analysis showed that postoperative numbness and Kelly assessment were significantly associated with hypercholesterolemia. Multivariate ana...Continue Reading

References

Jul 1, 1991·The Journal of Hand Surgery·P C FuchsL D Myers
May 1, 1990·The Journal of Hand Surgery·F SchuindJ L Pasteels
Apr 1, 1985·Plastic and Reconstructive Surgery·J NolanR C Schultz
Jun 4, 1983·Lancet·J L NadlerR Horton
Nov 1, 1984·The Journal of Hand Surgery·D P Green
Apr 1, 1994·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·S K al-GhazalJ McCann
Feb 1, 1994·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·C P KellyA M Jamieson
Mar 1, 1996·Journal of Occupational and Environmental Medicine·P A NathanK D Meadows
Jul 1, 1997·The Journal of Hand Surgery·B K BayR M Szabo
Dec 24, 1997·Occupational and Environmental Medicine·D L NordstromP M Layde
Jun 1, 1999·AJR. American Journal of Roentgenology·K MonagleR E Snyder
Jun 28, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·G LeonarduzziG Poli
Jun 27, 2002·The American Journal of Cardiology·Michael E Mendelsohn
Dec 6, 2003·Hypertension·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Jul 6, 2004·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·J M GeogheganR Hubbard
Jul 15, 2004·The Journal of Bone and Joint Surgery. American Volume·Anke M EttemaKai-Nan An
Nov 30, 2004·Clinical Biomechanics·U Chris UgbolueZong-Ming Li
Jun 7, 2005·Muscle & Nerve·Ken-Ichi Nakamichi, Shintaro Tachibana
Mar 25, 2006·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kazuaki ShimamotoUNKNOWN J-LIT Study Group
Jul 31, 2007·Acta Neurologica Scandinavica·K Balci, U Utku
Aug 29, 2007·Laboratory Investigation; a Journal of Technical Methods and Pathology·Gérald J Prud'homme
Apr 3, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Yuichi YoshiiPeter C Amadio
Jan 6, 2009·Neurology·R GelfmanJ C Stevens
Feb 13, 2010·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Shigeharu UchiyamaToshimitsu Momose
Oct 4, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Leo H VisserGeert Brekelmans
Jun 14, 2013·Muscle & Nerve·Mohammad-Hossein PourmemariRahman Shiri
Sep 10, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Takako ChikenjiPeter C Amadio
Jul 31, 2014·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Anne GingeryPeter C Amadio
Aug 26, 2014·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Shigeharu UchiyamaHiroyuki Kato
Aug 31, 2014·EMBO Molecular Medicine·Rose Q DoGregory G Schwartz
Oct 11, 2014·The Journal of Hand Surgery·Yasunori HattoriSatomi Koide
Jan 24, 2015·Nature Reviews. Immunology·Alan R Tall, Laurent Yvan-Charvet
May 20, 2015·The Journal of Hand Surgery·Young Hak RohGoo Hyun Baek
Oct 30, 2016·Electronic Physician·Sharareh RoshanzamirAlireza Dabbaghmanesh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.