PMID: 22353918Feb 23, 2012Paper

Hyperdense middle cerebral artery sign among patients with severe ischemic attack on ultra-early phase

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
Hong-song SongDong-sheng Fan

Abstract

To detect the frequency of hyperdense middle cerebral artery sign (HMCAS) among patients with severe ischemic attack (baseline NIHSS score ≥ 10) in the middle cerebral artery (MCA) territory within 3 hours after onset and compare the baseline characteristics and 90-day outcomes between the HMCAS (+) and HMCAS (-) groups. A total of 43 patients were evaluated with baseline clinical characteristics, laboratory tests and brain CT/MRI. Follow-up evaluation at the end of 90 days included the modified Rankin Scale (mRS), the Bathel Index (BI) and death. Ten out of forty-three (23.3%) patients were HMCAS (+).The 24-hour NIHSSS of HMCAS (+) group was significantly higher than that of HMCAS (-) group (20.2 ± 5.4 vs. 14.8 ± 7.2, P= 0.037). The follow-up scanning confirmed that all HMCAS (+) patients had larger MCA territory infarction and the ratio of large MCA territory infarction was significantly higher than that of HMCAS (-) group (100% vs. 39.1%, P = 0.001). There were no significant differences in age, gender, risk factors, time intervals, laboratory tests, 90-day functional outcomes between the two groups. The HMCAS (+) patients had notable deterioration 24 hours after onset and had more severe MCA infarction. HMCAS detected by no...Continue Reading

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