PMID: 549Nov 1, 1975

Hyperexcitability in the neural substrate of emotional behavior in cats after alcohol withdrawal. Evidence of a rapid development of alcohol dependence

Journal of Studies on Alcohol
M F MacDonnellB Davy

Abstract

Substantial and prolonged withdrawal hyperexcitability in the neural substrate for affective defense was revealed by behavioral and electrophysiological measures in cats exposed to moderate to heavy doses of alcohol for periods ranging from 6 to 72 hours. The data are interpreted as indicating a rapid development of physical dependence on alcohol in this portion of the central nervous system.

Citations

Apr 1, 1990·Digestive Diseases and Sciences·C WillsonA Keshavarzian
Jan 1, 1986·Physiology & Behavior·S L StoddardB E Levin
Feb 1, 1990·Alcoholism, Clinical and Experimental Research·A KeshavarzianC Willson
Aug 1, 1996·Alcoholism, Clinical and Experimental Research·K SchubertA Siegel
Nov 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·P PaquierJ J Martin

Related Concepts

Ethanol
Amygdaloid Structure
Metazoa
Behavior, Animal
Felis catus
Regret
Organum Vasculosum Laminae Terminalis
Hypothalamus, Middle
Withdrawal Symptoms
Substance-Related Disorders

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