Nov 1, 1975

Hyperexcitability in the neural substrate of emotional behavior in cats after alcohol withdrawal. Evidence of a rapid development of alcohol dependence

Journal of Studies on Alcohol
M F MacDonnellB Davy

Abstract

Substantial and prolonged withdrawal hyperexcitability in the neural substrate for affective defense was revealed by behavioral and electrophysiological measures in cats exposed to moderate to heavy doses of alcohol for periods ranging from 6 to 72 hours. The data are interpreted as indicating a rapid development of physical dependence on alcohol in this portion of the central nervous system.

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Mentioned in this Paper

Alcohol Withdrawal Syndrome
Ethanol
Behavior, Animal
Regret
Organum Vasculosum Laminae Terminalis
Withdrawal Symptoms
Neonatal Abstinence Syndrome
Neuronal Hyperexcitability
FAM64A
Defense Response

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