Hyperfamiliarity in patients with temporal lobe epilepsy

Epilepsy & Behavior : E&B
Jana AmlerovaPetr Marusic

Abstract

Hyperfamiliarity is a type of paramnesia characterized by an increased feeling of familiarity to unfamiliar faces. This dysfunction has been associated with frontal and temporal lobe pathology. The study investigated hyperfamiliarity in patients with temporal lobe epilepsy (TLE) by assessing their ability to recognize both familiar and unfamiliar faces. We evaluated 61 patients with pharmacoresistant TLE (33 right-sided, 28 left-sided) and 16 controls. The ability to recognize familiar faces was similar in patients and controls, although patients with left-sided TLE showed poorer performance in familiar face naming compared to both right-sided TLE patients and controls. Hyperfamiliarity was observed in a significantly higher number of patients with TLE compared to controls; in subgroup analysis, only right-sided TLE patients expressed hyperfamiliarity. Overall, patients with right-sided TLE showed more severe impairment compared to patients with left-sided TLE. It is proposed that hyperfamiliarity can be a relatively common symptom in patients with treatment-refractory TLE and right-sided focus.

References

Jan 29, 1992·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C A Heywood, A Cowey
Feb 1, 1992·Brain : a Journal of Neurology·J SergentB MacDonald
Feb 1, 1972·Journal of the Neurological Sciences·A L Benton, M W Van Allen
Apr 1, 1982·Neurology·A R DamasioG W Van Hoesen
Jan 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·J V HaxbyC L Grady
Dec 1, 1995·Journal of Clinical and Experimental Neuropsychology·B Hermann, M Seidenberg
Feb 11, 2000·Seizure : the Journal of the British Epilepsy Association·N EllisP Thompson
May 29, 2000·Trends in Cognitive Sciences·J V HaxbyM I Gobbini
Jun 22, 2000·Trends in Cognitive Sciences·T AllisonG McCarthy
Jul 9, 2003·Neurology·G GlosserN D Chiaravalloti
Jun 13, 2006·Epilepsy & Behavior : E&B·H Randall GriffithMichael Seidenberg
Jul 1, 2008·Epilepsy & Behavior : E&B·Krzysztof Bujarski, Michael R Sperling
Jan 31, 2009·Proceedings of the National Academy of Sciences of the United States of America·Reza RajimehrRoger B H Tootell
Mar 24, 2010·Neurology·O DevinskyT Thesen
Sep 15, 2010·Epilepsy & Behavior : E&B·Roberto MichelucciAnna F Marliani

❮ Previous
Next ❯

Citations

Jun 24, 2016·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Israel ContadorMaría Victoria Perea Bartolomé
Nov 22, 2016·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Pei Shi ChiaSimon Kang Seng Ting
Jul 15, 2015·PloS One·Elisa NegroMarco Tamietto

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

Epilepsy & Behavior : E&B
Roberto MichelucciAnna F Marliani
Epilepsy & Behavior : E&B
Krzysztof Bujarski, Michael R Sperling
© 2021 Meta ULC. All rights reserved