Hyperinflation using pressure support ventilation improves secretion clearance and respiratory mechanics in ventilated patients with pulmonary infection: a randomised crossover trial

The Australian Journal of Physiotherapy
Daniela Aires LemesFernando S Guimarães

Abstract

Is ventilator-induced hyperinflation in sidelying more effective than sidelying alone in removing secretions and improving respiratory mechanics in ventilated patients with pulmonary infection? Randomised crossover trial with concealed allocation and intention-to-treat analysis. 30 mechanically ventilated patients with pulmonary infection in an adult intensive care unit. The experimental intervention was 30 minutes of ventilator-induced hyperinflation using pressure support ventilation in sidelying; the control intervention was 30 minutes of sidelying. Participants received both interventions on the same day, with a five-hour washout period between them. Secretion clearance was measured as sputum volume retrieved during the intervention. Respiratory mechanics were measured as static compliance and total resistance of the respiratory system before and after the intervention. The experimental intervention cleared 1.3 ml (95% CI 0.5 to 2.2) more secretions than the control. After ventilator-induced hyperinflation in sidelying, respiratory compliance had increased 4.7 ml/cmH(2)O (95% CI 2.6 to 6.8) more than in sidelying alone. There was no difference in total resistance of the respiratory system between the interventions (mean dif...Continue Reading

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Citations

Jul 26, 2011·Heart & Lung : the Journal of Critical Care·Luciano M ChicaybanFernando S Guimarães
Aug 21, 2013·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·G CorkG Ntoumenopoulos
Mar 15, 2014·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Wagner da Silva NaueSilvia Regina Rios Vieira
Aug 17, 2018·International Journal of Evidence-based Healthcare·Guntaragorn HongrattanaChulee Ubolsakka-Jones
Jan 16, 2016·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Nirmal S SharmaEnrique Diaz-Guzman
Feb 9, 2012·Anaesthesia and Intensive Care·Diane DennisCharley Budgeon
Sep 12, 2012·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Juliana Savini Wey BertiAna Lucia Anjos Ferreira
Jun 29, 2018·Journal of Physical Therapy Science·Kyoushi MaseSachie Takashima
Jan 21, 2020·Nursing in Critical Care·Wendy JacobTracy Hebden-Todd
Jan 22, 2022·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Bruna Bampi ValerLuiz Alberto Forgiarini Júnior

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