Hyperjovinols A and B: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures

Journal of Natural Products
Konstantinos AthanasasDimitris Kletsas

Abstract

Two new and four known phloroglucinol derivatives were isolated from the dichloromethane extract of the Greek endemic plant Hypericum jovis. Their antioxidant activity was evaluated in vitro with the DPPH assay and in cell cultures using the DCFH-DA assay. All six compounds demonstrated significant antioxidant activity, while two of them possessed activity at a cellular level comparable to Trolox, protecting against ROS.

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Citations

Oct 4, 2012·Journal of Natural Products·Sebastian SchmidtJörg Heilmann
Jul 29, 2006·Natural Product Reports·Inder Pal Singh, Sandip B Bharate
Jul 30, 2014·Journal of Molecular Modeling·Rogelio A Delgado AlfaroLiliana Mammino
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Mar 8, 2016·Journal of Natural Products·Serge A T FobofouLudger A Wessjohann
Apr 15, 2008·Phytochemistry Letters·Sara L CrockettRudolf Bauer
May 15, 2009·Phytotherapy Research : PTR·Geneive E HenryNavindra P Seeram
Sep 16, 2014·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Eleni MavrogonatouDimitris Kletsas
Sep 5, 2009·Natural Product Research·H Raghu ChandrashekharP Vijayan
Jul 24, 2008·Dose-response : a Publication of International Hormesis Society·Harris PratsinisDimitris Kletsas
Oct 27, 2017·Anais Da Academia Brasileira De Ciências·Luciana C N LondeAlexandre B DE Oliveira
Dec 29, 2020·Natural Product Research·Jin-Yan XieXi-Tao Yan
Aug 29, 2018·Phytochemistry·Henrique BridiGilsane Lino von Poser
Aug 14, 2021·Planta medica·Maria-Eleni GrafakouHelen Skaltsa
Oct 26, 2018·Journal of Natural Products·Rolly G FuentesDavid G I Kingston

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