PMID: 6537493Jan 1, 1984Paper

Hyperlipidemia in swine immunized with lapinized vaccine and live swine plague virus

Polskie archiwum weterynaryjne
B Trawińska, K Andrychiewicz

Abstract

The purpose of the studies was to show the relationships between secondary hyperlipaemia and post-vaccination nephritis induced by lapinized vaccine with additional infection with the living virus of pig plague and the virus itself. CT, CF, LT, FFA and LP fractions were studied in the serum of blood taken from the vena cava cranialis from piglets weighing 30 - 40 kg, of the large white breed. In the animals of group 1, in the initial series a, series b - immunized with lapinized vaccine, series c - immunized and infected with virulent viruses, and also in group 2d - infected with the virus itself, the concentration of the lipids mentioned above was studied by the methods used elsewhere. The kidneys of the animals in series c and group 2d were examined histopathologically, staining them with h.e. and oil red solution neutral to fats. Multifocal inflammation reaction with the presence of fine-grained lipids were found. Particularly in group 2d the pathomorphological image, by its intensiveness and extensiveness pointed to severe inefficiency of kidneys. In series b and c of group 1a linear increase in the concentration of the lipids studies was found, as compared with series a. Hyperlipaemia was most distinctly marked in group 2d...Continue Reading

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