PMID: 3748475Jul 1, 1986Paper

Hypermetria in forelimb target-reaching after interruption of the inhibitory pathway from forelimb afferents to C3-C4 propriospinal neurones

Neuroscience Research
Bror AlstermarkA Lundberg

Abstract

Forelimb target-reaching in cats with a transection at C5/6 of the cortico- and rubrospinal tracts is known to depend on C3-C4 propriospinal neurones (PNs). An additional lesion transecting the dorsal column (DC) in C5/6, caudal to the C3-C4 PNs, gave pronounced hypermetria in lifting and protraction during target-reaching. If the additional DC lesion instead was made in C2, rostral to the C3-C4 PNs, there was only small hypermetria in lifting and none in protraction. It is postulated that the hypermetria after the C5/6 DC lesion is due to interruption of the inhibitory pathway from the forelimb to the C3-C4 PNs. It is suggested that feedback control from the forelimb of the premotoneurones is an integral part of the control of normal target-reaching.

Citations

Jan 1, 1993·Experimental Brain Research·B AlstermarkB Tantisira
Jun 1, 1984·Pflügers Archiv : European journal of physiology·M Illert, E Wiedemann
Apr 1, 1994·Journal of Neuroscience Methods·A Boczek-FunckeH Wiese
Feb 1, 1990·Neuroscience Research·E D Schomburg
Aug 1, 1991·Neuroscience Research·B AlstermarkL G Pettersson
May 3, 2000·The European Journal of Neuroscience·A Boczek-FunckeM Illert
May 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·M Nakajima, K Hirayama
Apr 25, 2012·Annual Review of Neuroscience·Bror Alstermark, Tadashi Isa
Mar 20, 2015·Multiple Sclerosis and Related Disorders·Kenji Kamogawa, Bungo Okuda
Apr 6, 2001·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·T Goto, Y Hoshino

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