Hypermobile Ehlers-Danlos syndrome and pregnancy

Obstetric Medicine
Akilandeswari Karthikeyan, Narayanaswamy Venkat-Raman

Abstract

Ehlers-Danlos syndromes are a clinically and genetically heterogeneous group of rare inherited connective tissue disorders. Hypermobile Ehlers-Danlos syndrome is one of the common types and not infrequently encountered in pregnancy. While, in the majority of women with hypermobile Ehlers-Danlos syndrome, the pregnancy is uncomplicated, it is important to be aware of the condition in view of potential complications such as recurrent joint dislocations and history of surgical joint stabilization procedures, secondary autonomic pain and postural orthostatic tachycardia syndrome. Increased awareness of the condition and a multi-disciplinary approach to the management of these women in pregnancy result in good outcome for the mother and the baby. We report the clinical characteristics and outcome of pregnancies in eight women with hypermobile Ehlers-Danlos syndrome and present a review of the literature with particular reference to management in a pregnant woman with joint hypermobility syndrome.

References

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Citations

Feb 7, 2020·BMJ Case Reports·Margarida CunhaInês Marques
Jun 2, 2020·Molecular Genetics & Genomic Medicine·Julie GomezHuda B Al-Kouatly
Sep 15, 2018·Obstetric Medicine·Michael P Carson, Stephen E Lapinsky
Apr 22, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Özgür Deniz TuranYasemin Turan
Jun 2, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Neekita PradhanD C Sundaresh
Jan 14, 2021·Journal of Translational Autoimmunity·Mareesa IslamM Eric Gershwin
Nov 14, 2021·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Natalie Blagowidow
Nov 21, 2021·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Mittal Patel, Vik Khullar

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Methods Mentioned

BETA
hysterectomy

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