PMID: 518179Dec 1, 1979Paper

Hyperparathyroid crisis: clinical and pathologic studies of 14 patients

Annals of Surgery
C A Wang, S W Guyton

Abstract

A study is presented of 14 patients with hyperparathyroid crisis treated at the Massachusetts General Hospital between 1964 and 1978. These patients showed diverse clinical manifestations that were indistinguishable from those in patients with pseudohyperparathyroidism. Their symptoms varied from progressive fatigue, malaise, and weakness to those related to the gastrointestinal and urinary tracts. The one biochemical alteration commonly found among these patients was the rapid increase in the serum calcium. There was a concomitant rise in the BUN in 50% of the patients and in the creatinine in 80%. The diagnosis was established by an elevated immunoreactive parathyroid hormone (PTH) level in all eight patients (100%) who had the radioimmunoassay; by the presence of subperiosteal resorption of the phalanges in six of the eight patients (75%); and in three of four patients (75%) by the loss of the lamina dura of the teeth. The 12 patients who had surgery all survived; the two who did not died. Thirteen patients (93%) had a neoplasm--an adenoma in 12 and a carcinoma in one. One patient had hyperplasia (7%). Nine patients (64%) received hypocalcemic drug therapy. The serum calcium temporarily fell to 12 mg/100 ml in five patients ...Continue Reading

References

Apr 1, 1978·Archives of Surgery·V G SchweitzerR H Nishiyama
May 1, 1977·Archives of Internal Medicine·M BoxerC A Wang
Jul 26, 1973·The New England Journal of Medicine·D PowellJ T Potts
May 1, 1966·Medicine·F W Lafferty
Feb 1, 1970·Cancer·C P PerliaS G Taylor
Sep 17, 1970·The New England Journal of Medicine·F R SingerJ T Potts
Nov 1, 1965·Metabolism: Clinical and Experimental·H O Heinemann
Jan 1, 1967·The Journal of Clinical Endocrinology and Metabolism·L M SherwoodJ T Potts
Aug 1, 1958·A.M.A. Archives of Internal Medicine·J S HEWSON
May 2, 1964·British Medical Journal·M R WILLS, G K MCGOWAN
Jan 11, 1964·Wiener medizinische Wochenschrift·H KUNZ
Dec 1, 1949·The American Journal of the Medical Sciences·S O WAIFE

❮ Previous
Next ❯

Citations

Aug 1, 1986·World Journal of Surgery·C WangA C Moncure
Feb 7, 2009·Journal of Endourology·Brian H EisnerMarshall L Stoller
Apr 15, 1989·BMJ : British Medical Journal·C J Hobbs
Feb 1, 1987·Postgraduate Medical Journal·C A KeelingD G Harloe
Jun 19, 2002·American Journal of Respiratory and Critical Care Medicine·Edward D ChanMarvin I Schwarz
Jan 7, 2011·Case Reports in Medicine·A S TahimP Sinha
Jun 14, 1980·Lancet·M Miller, D W Smith
May 27, 2008·Journal of the American College of Surgeons·Roy Phitayakorn, Christopher R McHenry
Oct 31, 2007·European Journal of Internal Medicine·G NtaiosD Karamitsos
Sep 1, 1989·The British Journal of Surgery·E SarfatiC Dubost
Nov 3, 2010·World Journal of Surgery·Lee F StarkerRobert Udelsman
Jun 18, 2014·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Lauren F GratianRandall P Scheri
Apr 19, 2012·ANZ Journal of Surgery·Magdalena A Biggar, Thomas W J Lennard
Sep 15, 2004·The European Journal of Surgery = Acta Chirurgica·Akin KuzucuHaluk Savli
May 1, 1984·Annals of Neurology·B M Patten, M Pages

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Surgery
T R Kelly, J Zarconi
Asian Journal of Surgery
Hsin-Hsien YuShih-Ming Huang
Archives of Internal Medicine
F Bayat-MokhtariR Pourmand
© 2021 Meta ULC. All rights reserved