Hyperpolarized 3He MR imaging of the lung: effect of subject immobilization on the occurrence of ventilation defects.

Academic Radiology
Jaime MataEduard de Lange

Abstract

To investigate immobilization-induced ventilation defects when performing hyperpolarized (3)He (H(3)He) magnetic resonance imaging (MRI) of the lung. Twelve healthy subjects underwent MRI of the lungs after inhalation of H(3)He gas at three time points: 1) immediately after having been positioned supine on the MRI scanner table, 2) at 45 minutes while remaining supine, 3) and immediately thereafter after having turned prone. All image sets were reviewed in random order by three independent, blinded readers who recorded number, location, and size of H(3)He ventilation defects. Scores were averaged for each time point and comparisons were made to determine change in number, location, and size of ventilation defects with time and positioning of the subject in the scanner. At baseline supine, there were small numbers of defects in the dependent (posterior) and nondependent (anterior) portions of the lung (P = .625). At 45 minutes, there was a significant increase in the mean number of ventilation defects/slice (VDS) for the dependent (P = .005) and a decrease for the nondependent lung portions (P = .021). After subjects turned prone, mean VDS for posterior defects decreased significantly (P = .011), whereas those for anterior defec...Continue Reading

References

Mar 1, 1991·Radiology·C J HeroldE A Zerhouni
Apr 20, 1999·Radiology·E E de LangeG D Cates
Mar 10, 2001·Journal of Magnetic Resonance Imaging : JMRI·T A AltesJ R Brookeman
Sep 19, 2001·The British Journal of Radiology·F W Wright
Jan 18, 2002·Journal of Applied Physiology·M J Rodríguez-NietoS Verbanck
Dec 28, 2002·Anesthesiology·Gerardo TusmanBurkhard Lachmann
Jul 23, 2004·Journal of Magnetic Resonance Imaging : JMRI·Stanislao FicheleJim M Wild
Sep 25, 2004·Journal of Magnetic Resonance Imaging : JMRI·Edwin J R van BeekEduard E de Lange

❮ Previous
Next ❯

Citations

Aug 19, 2009·Proceedings of the American Thoracic Society·Kiarash EmamiRahim R Rizi
Aug 13, 2011·Journal of Magnetic Resonance Imaging : JMRI·Nicholas J TustisonJames C Gee
Aug 21, 2013·Thorax·Sarah SvenningsenGrace Parraga
May 14, 2016·The European Respiratory Journal·Sarah SvenningsenGrace Parraga
Dec 23, 2017·The British Journal of Radiology·Agilo Luitger Kern, Jens Vogel-Claussen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

© 2021 Meta ULC. All rights reserved