Hypersalivation in temporal lobe epilepsy

Epilepsia
Jagdish ShahCraig Watson

Abstract

We sought to determine whether hypersalivation helps lateralize seizure onset during complex partial seizures of temporal lobe origin. Several clinical signs, which help lateralize seizure onset, have been reported in temporal lobe epilepsy (TLE). Increased salivation only occasionally has been reported as a manifestation of partial epilepsy. Of 590 consecutive patients admitted for video-EEG monitoring, either as a part of a presurgical evaluation of medically intractable epilepsy or for diagnosis and clarification of their paroxysmal symptoms, we identified 10 patients with ictal hypersalivation as a prominent manifestation of complex partial seizures. We reviewed the clinical features, scalp-sphenoidal video-EEG monitoring, intracarotid amytal (Wada) testing, hippocampal volumetric magnetic resonance imaging (MRI), and fluorodeoxyglucose-positron emission tomography (FDG-PET) scans of these patients. Of the 10 patients with ictal hypersalivation, seven patients had nondominant/right TLE, and three patients had dominant/left TLE. All patients had hippocampal atrophy on volumetric MRI. Eight of the 10 patients underwent standard temporal lobectomy with amygdalohippocampectomy (six right, two left). All of the operated-on patie...Continue Reading

References

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Citations

Feb 12, 2009·Developmental Medicine and Child Neurology·Corrie E ErasmusJan J Rotteveel
Apr 14, 2015·Experimental Neurology·James D'AmourHelen E Scharfman
Jul 20, 2010·Seizure : the Journal of the British Epilepsy Association·S BroicherH Jokeit
Sep 15, 2009·Epilepsy Research·Judith M HoffmannAiling A Kleefuss-Lie
Jan 17, 2013·Journal of Clinical Neurology·Krikor Tufenkjian, Hans O Lüders
Jul 14, 2012·Journal of Feline Medicine and Surgery·An E VanhaesebrouckFernando Constantino-Casas
Jun 18, 2017·Epilepsy & Behavior : E&B·Michihiko TakasuAkihisa Okumura
May 3, 2018·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Lisanne E M BreuerAlbert P Aldenkamp
Feb 26, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Christoph BaumgartnerSusanne Pirker

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