PMID: 9534923Apr 16, 1998Paper

Hypersensitivity pneumonitis due to an ultrasonic humidifier

Allergy
J A Alvarez-FernándezE Losada

Abstract

We describe a woman with hypersensitivity pneumonitis that was related to using a home ultrasonic humidifier. A micronodular infiltrate was seen in her chest radiograph. The inhalation challenge test was performed with the humidifier, and she exhibited a positive response. The cultures of the humidifier water grew Candida albicans, Rhodotorula spp., and Aspergillus spp. The test for precipitating antibodies against the humidifier water gave a positive response, and specific IgG, IgM, and IgA antibodies against extracts of A. fumigatus, C. albicans, and Rhodotorula spp. were demonstrated in the patient's serum by ELISA. A strong, dose-dependent inhibition of Rhodotorula IgG-ELISA by humidifier water was observed, suggesting that Rhodotorula might be the cause of hypersensitivity pneumonitis in this patient.

References

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Citations

Nov 11, 1999·American Journal of Respiratory and Critical Care Medicine·R S WrightP Harber
Jan 20, 2005·American Journal of Respiratory and Critical Care Medicine·Jordan N FinkYasuyuki Yoshizawa
Feb 3, 2016·Respiratory Medicine·M L Millerick-MayK D Rosenman
Oct 30, 2012·Revue des maladies respiratoires·D CaillaudK Horo
Oct 10, 2009·Archivos de bronconeumología·Carlos SerranoCésar Picado
May 16, 2009·Archivos de bronconeumología·Alicia Enríquez-MatasRosario Melchor
Mar 13, 2014·The Journal of Investigative Dermatology·Sarah T ArronMichael L Whitfield
Jun 14, 2005·Respiratory Medicine·Dirk KoschelDietrich Müller-Wening
Nov 11, 2006·American Journal of Industrial Medicine·Ki Moon BangGirija Syamlal

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