PMID: 8939163Nov 1, 1996Paper

Hypersensitivity pneumonitis in workers exposed to esparto grass (Stipa tenacissima) fibers

The Journal of Allergy and Clinical Immunology
M HinojosaA Sueiro

Abstract

Esparto grass (Stipa tenacissima), which is commonly found in the Mediterranean countries, has a wide variety of uses. Five stucco makers who had cough, dyspnea, malaise, and fever after exposure to esparto fiber used in their jobs showed a significant decrease in symptoms when they were away from work. Precipitating antibodies against an esparto extract were found in the sera of all patients. Specific IgG antibodies against the esparto extract were also demonstrated in all patient sera, as were IgG antibodies to Aspergillus fumigatus and thermophilic microorganisms (Micropolyspora faeni and Thermoactinomyces vulgaris) by means of an ELISA method. Esparto activity was inhibited in different ranges by the above antigens by inhibition ELISA. Only A. fumigatus could be identified after microbiologic evaluation of the esparto fiber samples. After inhalation challenge tests were performed with esparto extracts, all patients showed significant decreases in forced vital capacity, transfer lung CO, and PaO2 blood gas from baseline values. Fever, chills, malaise, dry cough, tachycardia, tachypnea, and rales on chest auscultation were also observed in all patients. Findings from bronchoalveolar lavage were suggestive of allergic alveolit...Continue Reading

References

Jan 1, 1978·Annals of Internal Medicine·P Y HoloyeC W Bedrossian
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Citations

Aug 24, 2000·Allergy·E González-ManceboF León
Apr 16, 1998·Allergy·J A Alvarez-FernándezE Losada
Jul 29, 1998·The Journal of Allergy and Clinical Immunology·S QuirceM Yoldi
Jul 14, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·María J RodrigoJorge Martínez
Jun 18, 2002·Chest·Ayman O Soubani, Pranatharthi H Chandrasekar
Mar 1, 2019·Medical Mycology·Raquel SabinoMalcolm Richardson
May 22, 2003·Allergy·C Martin-GarciaP Berges
Jan 5, 2007·Revue des maladies respiratoires·I ThaonJ C Dalphin

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