Hyperspectral imaging system in the delineation of Ill-defined basal cell carcinomas: a pilot study

Journal of the European Academy of Dermatology and Venereology : JEADV
M SalmivuoriM Grönroos

Abstract

Basal cell carcinoma (BCC) is the most common skin cancer in the Caucasian population. Eighty per cent of BCCs are located on the head and neck area. Clinically ill-defined BCCs often represent histologically aggressive subtypes, and they can have subtle subclinical extensions leading to recurrence and the need for re-excisions. The aim of this pilot study was to test the feasibility of a hyperspectral imaging system (HIS) in vivo in delineating the preoperatively lateral margins of ill-defined BCCs on the head and neck area. Ill-defined BCCs were assessed clinically with a dermatoscope, photographed and imaged with HIS. This was followed by surgical procedures where the BCCs were excised at the clinical border and the marginal strip separately. HIS, with a 12-cm2 field of view and fast data processing, records a hyperspectral graph for every pixel in the imaged area, thus creating a data cube. With automated computational modelling, the spectral data are converted into localization maps showing the tumour borders. Interpretation of these maps was compared to the histologically verified tumour borders. Sixteen BCCs were included. Of these cases, 10 of 16 were the aggressive subtype of BCC and 6 of 16 were nodular, superficial o...Continue Reading

References

Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A Neil Crowson
Apr 28, 2006·The Australasian Journal of Dermatology·David Burdon-Jones, Peter W Thomas
May 10, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Philip R CohenBruce R Nelson
Aug 1, 2008·The Journal of Investigative Dermatology·Naomi M Richmond-SinclairAdèle C Green
Sep 25, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Francisco BobadillaGregor B E Jemec
Nov 21, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Anokhi Jambusaria-PahlajaniJoel M Gelfand
Feb 14, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Roberto BettiCarlo Crosti
Oct 5, 2010·Plastic and Reconstructive Surgery·Yusuf GullethBrian R Gastman
Nov 29, 2011·Dermatologic Clinics·Randie H Kim, April W Armstrong
Jun 26, 2012·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Mansour Nassiri-KashaniAlireza Firooz
Jul 5, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·E A W WolberinkM J P Gerritsen
Sep 20, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·K Kamyab-HesariN Aghazadeh
Oct 23, 2012·Facial Plastic Surgery Clinics of North America·Burak Ömür CakirCemal Cingi
Jan 9, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Katie Xiaoyi WangDaniel M Siegel
Mar 19, 2013·Clinical and Experimental Dermatology·N J LevellD C Greenberg
Sep 17, 2013·Lasers in Surgery and Medicine·Noora Neittaanmäki-PerttuErna Snellman
Jan 21, 2014·Journal of Biomedical Optics·Guolan Lu, Baowei Fei
Apr 12, 2014·European Journal of Dermatology : EJD·Myrto TrakatelliNicole Basset-Seguin
Sep 30, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Eva van LooNicole W J Kelleners-Smeets
Nov 15, 2014·Acta Dermato-venereologica·Noora Neittaanmäki-PerttuErna Snellman
Oct 27, 2015·The British Journal of Dermatology·M VenturiniP G Calzavara-Pinton
Nov 12, 2015·Acta Dermato-venereologica·Ann-Sofie HolmHans Christian Wulf

❮ Previous
Next ❯

Citations

Aug 17, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·T GreywalS B Jiang
Aug 25, 2021·Journal of Biophotonics·Mihaela Antonina Calin, Sorin Viorel Parasca

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.