PMID: 8268893Nov 1, 1993Paper

Hypertension and diabetes

Clinical and Experimental Hypertension : CHE
P Hamet


Co-presentation of hypertension and diabetes leads to a significantly greater increase of cardiovascular mortality than each disease separately. Hypertension appears to be not only a complication of diabetes but apparently also shares a common pathogenetic mechanism, particularly in non-insulin dependent diabetes. Recent data suggest alterations in the nocturnal decline of blood pressure in diabetics, which together with microalbuminuria, may prove to be a predictor of nephropathy and hypertension. When hypertension occurs in diabetics, it requires a vigorous therapeutic approach. Nevertheless, the presence of diabetes modifies the requirement for first line therapy, particularly with respect to potential alterations of metabolic homeostasis in order to effectively prevent cardiovascular complications.


Sep 1, 1992·Diabetes Care·S Strowig, P Raskin
Oct 1, 1992·Journal of the American Society of Nephrology : JASN·L M Resnick
Jul 1, 1992·Diabetes Care·B H Brouhard
Jun 1, 1991·Diabetes Care·P P Stein, H R Black
Jun 1, 1991·Diabetes Care·H I Tjoa, N M Kaplan
Mar 1, 1991·Diabetes Care·P Weidmann, P Ferrari
Dec 15, 1990·Annals of Internal Medicine·B K Demarie, G L Bakris
Apr 7, 1990·BMJ : British Medical Journal·S BjörckM Aurell
Dec 26, 1985·The New England Journal of Medicine·Y TagumaY Sasaki

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