Hypertension in African Americans

Current Cardiology Reports
Nomsa Musemwa, Crystal A Gadegbeku

Abstract

African Americans are over-burdened with hypertension resulting in excess morbidity and mortality. We highlight the health impact of hypertension in this population, review important observations regarding disease pathogenesis, and outline evidence-based treatment, current treatment guidelines, and management approaches. Hypertension accounts for 50% of the racial differences in mortality between Blacks and Whites in the USA. Genome-wide association studies have not clearly identified distinct genetic causes for the excess burden in this population as yet. Pathophysiology is complex likely involving interaction of genetic, biological, and social factors prevalent among African Americans. Non-pharmacologic and pharmacologic therapy is required and specific treatment guidelines for this population are varied. Combination therapy is most often necessary and single-pill formulations are most successful in achieving BP targets. Racial health disparities related to hypertension in African Americans are a serious public health concern that warrants greater attention. Multi-disciplinary research to understand the inter-relationship between biological and social factors is needed to guide successful treatments. Comprehensive care strate...Continue Reading

References

Aug 31, 1989·The New England Journal of Medicine·A P RocchiniM Martin
Jan 1, 1994·Journal of Hypertension·S Madhavan, M H Alderman
Mar 1, 1996·Hypertension·M H Weinberger
Jul 1, 1996·Clinical Pharmacology and Therapeutics·N J BrownM R Griffin
Oct 1, 1996·American Journal of Public Health·N Krieger, S Sidney
Jun 8, 2000·Annals of the New York Academy of Sciences·J E HallJ R Henegar
Jan 4, 2001·The New England Journal of Medicine·F M SacksUNKNOWN DASH-Sodium Collaborative Research Group
Mar 7, 2001·Kidney International·D A PriceN K Hollenberg
May 3, 2001·The New England Journal of Medicine·C W YancyUNKNOWN U.S. Carvedilol Heart Failure Study Group
Jun 21, 2001·JAMA : the Journal of the American Medical Association·L Y AgodoaUNKNOWN African American Study of Kidney Disease and Hypertension (AASK) Study Group
Mar 19, 2002·Hypertension·Michel E SafarGérard M London
Apr 8, 2003·Journal of the American College of Cardiology·John M FlackElijah Saunders
May 2, 2003·Current Hypertension Reports·Deborah A Price, Naomi D L Fisher
Oct 24, 2003·American Journal of Hypertension·Mari Konishi NishizakaDavid A Calhoun
Feb 12, 2004·Congestive Heart Failure·Shawna Nesbitt, Ronald G Victor
Mar 19, 2004·Journal of the American College of Cardiology·Stevo JuliusJackson T Wright
Oct 20, 2004·Annals of Internal Medicine·Lizzy M BrewsterJos Kleijnen
Apr 7, 2005·JAMA : the Journal of the American Medical Association·Jackson T WrightUNKNOWN ALLHAT Collaborative Research Group
Dec 13, 2005·Kidney International. Supplement·Giuseppe RemuzziPiero Ruggenenti
Sep 27, 2006·European Heart Journal·Stephane LaurentUNKNOWN European Network for Non-invasive Investigation of Large Arteries
Mar 27, 2007·American Journal of Preventive Medicine·Sarah Stark CasagrandeTiffany L Gary
May 24, 2007·Current Hypertension Reports·Sripal BangaloreFranz H Messerli
Nov 6, 2007·The Journal of Clinical Hypertension·Elijah SaundersWill A Sullivan
Jan 24, 2008·Reproductive Sciences·Eugenia Mata-Greenwood, Dong-Bao Chen

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Citations

Feb 1, 2018·Health Services Research and Managerial Epidemiology·Olufunmilola AbrahamAlison Feathers
Dec 12, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rachel C DrewJeanie Park
Jun 5, 2020·Circulation Research·Lindsay Fernández-RhodesKari E North
Nov 7, 2019·Nutrients·Meghan C ZimmerCristina Barroso
Jul 17, 2020·Frontiers in Genetics·Ebony Shah-WilliamsTodd C Skaar
Sep 3, 2020·Journal of Human Hypertension·Elliot N Mahlof, John D Bisognano
Aug 17, 2019·Jornal brasileiro de nefrologia : ʹorgão oficial de Sociedades Brasileira e Latino-Americana de Nefrologia·Christine Zomer Zomer Dal MolinDaisson Jose Trevisol
Dec 29, 2020·JAMA Internal Medicine·Radhika RastogiMichael B Rothberg
Mar 2, 2021·Hypertension·Arnaud D KazeJustin B Echouffo-Tcheugui
Jun 25, 2021·American Journal of Hypertension·Arnaud D KazeJustin B Echouffo-Tcheugui
Jun 27, 2021·Journal of Hypertension·Arnaud D KazeJustin B Echouffo-Tcheugui
Jan 29, 2022·Journal of Racial and Ethnic Health Disparities·Goutham Rao, Susan Connor

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