Hypertension in high-risk patients: beware of the underuse of effective combination therapy (results of the PRATIK study)

Journal of Hypertension
J AmarPRATIK study investigators

Abstract

To determine whether blood pressure control in a general practice setting is influenced by the presence of additional risk factors, and to analyse the role of antihypertensive therapy in this relationship. A cross-sectional study was conducted with a sample of 3153 general practitioners. Primary care. The first five hypertensive patients presenting at the practitioner's office were included. Cardiovascular risk factors, antihypertensive drugs and cardiovascular history were reported. Blood pressure was measured. The analysis was conducted in treated patients who were divided in three groups: no other risk factors (group I); 1-2 risk factors (group II); 3 or more risk factors or target-organ damage or diabetes or associated cardiovascular disease (group III). Data were available for all variables in the 14 066 treated hypertensive individuals who form the basis of this report. Blood pressure control had been achieved in a lower percentage of individuals in group III (27%) than in group I (42.9%). To control hypertension, combination therapies were more frequently required in group III (55.8%) than in group II (43.5%) or group I (34.2%). Among individuals with uncontrolled hypertension, about 39% of patients in group III were rec...Continue Reading

References

Sep 6, 1986·British Medical Journal·J C PetrieM de Swiet
Nov 1, 1994·American Journal of Public Health·D H StockwellM H Alderman
Jun 17, 1998·JAMA : the Journal of the American Medical Association·M Moser
Dec 31, 1998·The New England Journal of Medicine·D R BerlowitzM A Moskowitz
Sep 15, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R W Schrier
Apr 6, 2001·Journal of Hypertension·J AmarJ Ferrières

❮ Previous
Next ❯

Citations

Nov 24, 2006·International Urology and Nephrology·George S Stergiou
Jul 21, 2006·Journal of Human Hypertension·J InamoT Lang
Feb 28, 2007·Vascular Health and Risk Management·Daria RoccatagliataUNKNOWN Collaborative Group Risk and Prevention Study
Jan 6, 2005·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Sverre E KjeldsenSuzanne Oparil
Nov 13, 2008·Current Problems in Cardiology·Michael D Faulx, Gary S Francis
Mar 10, 2010·Journal of Internal Medicine·L MechtouffUNKNOWN REACH Registry Investigators
Aug 12, 2009·Archives of Cardiovascular Diseases·Robert NicodèmeThierry Lang
Feb 10, 2012·American Journal of Hypertension·Nathan D WongStanley S Franklin
Oct 2, 2003·The Annals of Pharmacotherapy·Khalid A Jassim Al KhajaAwatif H H Damanhori
May 25, 2004·Stroke; a Journal of Cerebral Circulation·Jacques AmarUNKNOWN ECLAT1 Study Investigators
May 26, 2006·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·Bernard Waeber
Jun 1, 2007·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·Jacques Amar
Oct 20, 2009·Journal of Hypertension·Giuseppe ManciaUNKNOWN European Society of Hypertension
Dec 4, 2009·Expert Review of Cardiovascular Therapy·Yves LacourcièreRita Samuel
Jun 5, 2003·Journal of Hypertension·Jacques AmarJean Pierre Cambou
Aug 22, 2003·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·Bernard Waeber
Oct 31, 2003·Expert Opinion on Drug Safety·Renke Maas, Rainer H Böger
Mar 12, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Xin ZhengHongyun Wang
May 26, 2005·Joint Commission Journal on Quality and Patient Safety·Richard AdairSarah C Gantert

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.