Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study.

Journal of Veterinary Internal Medicine
Laura Pearl ColeKaren Humm

Abstract

Systemic hypertension (SH) is a potential complication of acute kidney injury (AKI) in dogs. To describe the prevalence of SH and hypertensive retinopathy in dogs with AKI, to investigate the relationship between SH and severity of AKI and to assess possible factors associated with SH. Fifty-two dogs with AKI. Prospective observational study of dogs presenting to a tertiary referral center that fulfilled the International Renal Interest Society (IRIS) guidelines for the diagnosis of AKI. Systolic blood pressure measurement, urine protein/creatinine ratio (UPCR), urine output, presence of hypertensive retinopathy and fluid overload (FO), survival to discharge and duration of hospitalization were subsequently assessed. The prevalence of SH was calculated and the relationship between SH and recorded factors was examined by nonparametric statistics. The prevalence of SH (≥160 mm Hg) on admission or during hospitalization was 75% (39/52) and in 56% (22/39) of cases this was severe (≥180 mm Hg). Sixteen percent (7/43) of dogs had evidence of hypertensive retinopathy and 77% (24/31) dogs had UPCR >0.5. Forty-two percent (22/52) dogs had FO on admission or during hospitalization. There was no association between SH and IRIS AKI grade, ...Continue Reading

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Citations

Jul 17, 2021·Frontiers in Veterinary Science·Bernie Hansen

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Methods Mentioned

BETA
urine measurement
urine collection

Software Mentioned

SPSS Statistics

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