Hypertensive encephalopathy in childhood. Diagnostic problems

A J van VughtJ Willemse


Oppenheimer and Fischberg's vasoconstriction-hypothesis on the pathogenesis of hypertensive encephalopathy was subsequently supported by animal experiments. Later on the role of decompensation of the autoregulatory mechanism of the cerebral blood flow was revealed. The transient symptomatology comprises headache, seizures, focal cerebral symptoms (hemiplegia etc.), visual disturbances, mental disorders, papiledema etc. The age-dependency of the influence of edema is probably expressed by the predominance of seizures in childhood and the long duration of the symptoms in our third and fourth patient. The differentiation between hypertensive encephalopathy and a local complication of hypertension (hemorrhage) can be difficult, not at least because the first disturbance may be followed by the second (patient 3). Hypertension is not always present as initial symptom (patient 1 and 2). Hence a series of blood pressure readings is required in acute cerebral incidents in childhood. Steroid-treatment may lead, especially in patients suffering from a hypocomplementemic form of membranoproliferative glomerulonephritis, to a sudden rise of the blood pressure and subsequently to hypertensive encephalopathy (patients 2 and 3). Hypertensive e...Continue Reading


Dec 1, 1982·Archives of Disease in Childhood·R S TrompeterC Chantler
Nov 1, 1979·European Journal of Pediatrics·M UhariO Koskimies
Jan 1, 1993·European Journal of Pediatrics·K SchärerW Rascher
Aug 9, 2003·Expert Opinion on Drug Safety·D Blowey
May 1, 1996·Journal of Child Neurology·R R Wright, K D Mathews

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Brain Pathology
Hypertensive Disease

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