Hyperuricemia. When and how to treat?

Der Internist
M A Reuss-Borst

Abstract

The prevalence of (asymptomatic) hyperuricemia and gout has substantially increased in recent decades. This development is due to fundamental lifestyle changes, dramatically rising prevalence of obesity and metabolic syndrome, as well as the increasing age of patients. Therefore, medical treatment of hyperuricemia has regained interest in recent years, in particular since after decades of therapeutic stagnation, new treatments of hyperuricemia have been approved or are currently being investigated in clinical trials. European and American guidelines/recommendations for treatment of hyperuricemia and gout have been updated and revised. Furthermore, the role of asymptomatic hyperuricemia as an (independent) cardiovascular risk factor is again under debate. This article provides assistance in integrating our present knowledge in a therapeutic context and summarizes currently recommended treatment strategies.

References

Sep 5, 2002·Arthritis and Rheumatism·Fernando Perez-RuizAna Ruibal
Jan 22, 2005·Seminars in Nephrology·Richard J JohnsonWilliam J Oliver
Dec 13, 2005·The New England Journal of Medicine·Michael A BeckerNancy Joseph-Ridge
Apr 8, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Chaitanya A SarawateAlan W Bakst
Mar 28, 2008·Pharmacotherapy·Becky A BriesacherK Arnold Chan
Aug 30, 2008·JAMA : the Journal of the American Medical Association·Daniel I FeigRichard J Johnson
Mar 31, 2009·Arthritis Research & Therapy·Leslie R HarroldIra S Ockene
Apr 8, 2010·Arthritis Research & Therapy·Michael A BeckerChristopher Lademacher
Apr 20, 2010·Clinical Rheumatology·Tim L JansenMichael Doherty
Jun 12, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Marian GoicoecheaJosé Luño
Oct 6, 2010·The American Journal of Medicine·Vidula BholeHyon Choi
Mar 15, 2011·British Journal of Clinical Pharmacology·Li WeiThomas M MacDonald
Sep 8, 2011·Arthritis and Rheumatism·Fernando Perez-RuizLoreto Carmona
Mar 3, 2012·The Journal of Rheumatology·Aryeh M Abeles
Oct 27, 2012·The American Journal of Medicine·Thomas H TaylorTodd A Mackenzie
Jan 25, 2013·Annals of the Rheumatic Diseases·Yuqing ZhangHyon Choi
Apr 9, 2013·QJM : Monthly Journal of the Association of Physicians·A G StackH T Nguyen
May 17, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Akira SezaiMotomi Shiono
Jan 17, 2014·Annals of the Rheumatic Diseases·Chang-Fu KuoMichael Doherty
Jan 23, 2014·Arthritis & Rheumatology·Saskia BrudererChristoph R Meier
Apr 3, 2014·The Journal of Rheumatology·Gerald D LevyT Craig Cheetham
Sep 3, 2014·The Journal of Rheumatology. Supplement·Mariano AndrésLoreto Carmona
Dec 24, 2014·JAMA : the Journal of the American Medical Association·Chang-Fu KuoMichael Doherty
Mar 6, 2015·Annals of the Rheumatic Diseases·Na LuHyon K Choi

❮ Previous
Next ❯

Citations

Mar 4, 2020·Der Nervenarzt·S Knecht, T Schmidt-Wilcke
Jun 24, 2021·Journal of Food Science·Hongling LiHaitao Li

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Cardiovascular Risk Prediction

Cardiovascular risk prediction models based on classical risk factors identified in epidemiological studies are useful in primary prevention of cardiovascular disease in individuals. Here is the latest research.

Related Papers

Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
Pietro Cirillo, Loreto Gesualdo
Medicina clínica
J García Puig, L Miguel Ruilope
Nihon rinsho. Japanese journal of clinical medicine
T YamanouchiI Akaoka
© 2022 Meta ULC. All rights reserved