PMID: 8599009Jan 1, 1996Paper

Hypervitaminosis A as a complication of treatment for neuroblastoma

Pediatric Radiology
L E GrissomG A Mandell

Abstract

A case of hypervitaminosis A (HVA) as a complication of therapy for stage-IV neuroblastoma is presented. The patient was randomized to a trial of 13-cis -retinoic acid (a vitamin A-related compound) after completing routine chemotherapy. This acid was given as a means of maturing potential minimal residual disease. A routine follow-up bone scan revealed areas of increased activity, initially along the midshaft of the right ulna and subsequently bilaterally, which were ultimately found to be due to HVA. Hypervitaminosis A has not been previously reported in this setting, and awareness of the condition is important in centers where this treatment is contemplated.

References

Apr 1, 1985·AJR. American Journal of Roentgenology·J H Miller, I I Hayon
Apr 1, 1985·AJR. American Journal of Roentgenology·R GreeneH Janstsch
Jul 1, 1943·The Biochemical Journal·K Rodahl, T Moore

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Citations

Aug 28, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·D J Roebuck
Oct 8, 2008·Pediatric Blood & Cancer·Aurélien MarabelleJustyna Kanold
Apr 29, 2015·Pediatric Dermatology·Shekhar NeemaManas Chatterjee
Feb 14, 2006·The American Journal of Clinical Nutrition·Kristina L Penniston, Sherry A Tanumihardjo
Jun 22, 2000·Nutrition Reviews·N Binkley, D Krueger

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