HypoCol (red yeast rice) lowers plasma cholesterol - a randomized placebo controlled study

Scandinavian Cardiovascular Journal : SCJ
Martin Prøven BogsrudKjetil Retterstøl

Abstract

The primary endpoint in our study was to investigate the effect of a red yeast rice (RYR) product on plasma lipids. A randomized, double-blind, placebo controlled study was performed. Patients were randomized to either RYR (HypoCol, 4 capsules/day) (n=22) or placebo (n=20) for 16 weeks. Inclusion criteria were male or female, 18-75 years, LDL-cholesterol between 3.0 and 6.0 mmol/L, fasting triglyceride level less than 4.5 mmol/L. Patients receiving RYR experienced a significant reduction in LDL-cholesterol (23.0%) and total cholesterol (15.5%) compared to placebo after 16 weeks of treatment (p<0.001). The tested red yeast rice product demonstrated a significant cholesterol lowering effect compared to placebo, and was well tolerated in this Caucasian population.

References

Feb 16, 1999·The American Journal of Clinical Nutrition·D HeberV L Go
May 1, 2001·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·D HeberV L Go
Nov 20, 2002·Transplantation·G V Ramesh PrasadSalma Bhaloo
Nov 9, 2004·Atherosclerosis. Supplements·Akira Endo
Jan 10, 2006·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Zhaoping LiDavid Heber
Jun 17, 2009·Annals of Internal Medicine·David J BeckerDaniel J Rader

❮ Previous
Next ❯

Citations

Nov 10, 2010·Current Atherosclerosis Reports·Ram Y Gordon, David J Becker
Feb 8, 2011·Current Diabetes Reports·Tanya Lee, Jean-Jacques Dugoua
Jun 25, 2013·Maturitas·Antonio González-SarríasJuan Carlos Espín
Nov 8, 2012·Complementary Therapies in Medicine·Clinton W Yang, Shaker A Mousa
Mar 6, 2012·Journal of Clinical Lipidology·Mitchell KarlJohn Brejda
Jul 30, 2011·The Urologic Clinics of North America·Mark A Moyad, Laurence H Klotz
Mar 10, 2016·Journal of Clinical Pharmacy and Therapeutics·Yi Chin Ong, Zoriah Aziz
Mar 14, 2016·Clinics and Research in Hepatology and Gastroenterology·Filip J CouturierVeronique M Verhoeven
Dec 17, 2014·Journal of Clinical Lipidology·Patrick M MoriartySimon Li
Apr 4, 2016·World Journal of Microbiology & Biotechnology·Seema Patel
Feb 19, 2013·Journal of Clinical Lipidology·Lindsey ChildressMatthew K Ito
Aug 12, 2014·BioMed Research International·Tung-Ting ShamShun-Wan Chan
Feb 7, 2014·Critical Reviews in Food Science and Nutrition·Gu ChenShang-Tian Yang
Feb 2, 2019·Current Pharmaceutical Design·Michele ScognamiglioClaudio Napoli
Aug 3, 2018·EFSA Journal·UNKNOWN EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)Matthew Wright
Jan 1, 2016·Journal of Food and Drug Analysis·Ming-Tzai ChenShi-Wern Chien
Mar 16, 2019·The American Journal of Chinese Medicine·Tien-Ju WangSien-Hung Yang
Jun 11, 2020·Food Research International·Gitishree DasJayanta Kumar Patra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.