PMID: 15235149Jul 6, 2004Paper

Hypoglycemic activity of inorganic constituents in Eugenia jambolana seed on streptozotocin-induced diabetes in rats

Biological Trace Element Research
K RaviS Subramanian

Abstract

Medicinal herbs used in indigenous medicines for the management of diabetes mellitus contain both organic and inorganic constituents. Some of these inorganic trace elements possess antidiabetic properties, which accounts for the activity of medicinal herbs. The aim of this study was to analyze the inorganic trace elements present in Eugenia jambolana seeds and to evaluate the hypoglycemic activity of the inorganic part of E. jambolana seeds on streptozotocin-induced diabetes. The seeds of E. jambolana seeds were reduced to ash and the inorganic elements present were assayed. The hypoglycemic efficacy of the inorganic part was tested by the glucose tolerance test on streptozotocin-induced diabetes. Elements such as zinc, chromium, vanadium, potassium, and sodium, possessing hypoglycemic activity, were present in the seed. The E. jambolana seed ash-treated diabetic rats exhibited normoglycemia and better glucose tolerance. The conclusion that the inorganic constituents might play a important role in the antidiabetic nature E. jambolana seeds was reached.

Citations

Feb 19, 2010·Biological Trace Element Research·Sivasankari S ManiKandaswamy Muthusamy
Oct 4, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Manjeshwar S BaligaSrinath Rao
Jun 3, 2005·Biological & Pharmaceutical Bulletin·Dhanasekar Sathishsekar, Sorimuthu Subramanian
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Menakshi BhatBimba N Joshi
May 9, 2006·Journal of Ethnopharmacology·Pulok K MukherjeePeter J Houghton
Aug 2, 2005·Journal of Ethnopharmacology·Antônio Carlos P OliveiraMárcio M Coelho
Jun 4, 2016·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Sally A El AwdanManal Badawi
Dec 18, 2018·3 Biotech· Bindu Jacob, Narendhirakannan R T

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