Jan 1, 1985

Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis

Scandinavian Journal of Rheumatology
K S Christensen


A 62-year-old woman with Sjögren's syndrome, distal renal tubular acidosis and hypokalemic muscle paralysis is described. The sicca syndrome was nearly subclinical and went unrecognized for several years. The main and first manifestation to be expressed was that of hypokalemic muscle paralysis secondary to renal tubular acidosis. In the last decade several reports have appeared indicating that renal tubular acidosis is associated with Sjögren's syndrome. The data in this report support the view that adult onset distal renal tubular acidosis is often a disorder of an autoimmune disease, frequently that of Sjögren's syndrome. The complications to renal tubular acidosis such as hypokalemic muscle paralysis or chronic muscle weakness, nephrolithiasis, and osteomalacia can be avoided if the diagnosis of renal tubular acidosis is made and corrective alkali therapy is maintained.

  • References8
  • Citations8


Mentioned in this Paper

Todd Paralysis
Waardenburg Syndrome
Spiro von ct
Renal Tubular Acidosis
Renal Tubular Acidosis, Type II
Distal Renal Tubular Acidosis
Carbonic Acid Ions
Potassium bicarbonate
Potassium Compounds

About this Paper

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.