PMID: 375794Jun 1, 1979Paper

Hypomagnesemia and renal magnesium wasting in patients receiving cisplatin

Annals of Internal Medicine
R L Schilsky, T Anderson

Abstract

We studied renal function and serum electrolytes in 51 patients receiving cisplatin chemotherapy by retrospectively reviewing the charts of 44 patients and prospectively following seven patients. Hypomagnesemia developed in 23 of 44 evaluable patients who were receiving cisplatin. We documented inappropriate renal magnesium wasting in four patients. Two patients required hospitalization for symptomatic hypomagnesemia. We conclude that cisplatin can induce a renal tubular defect in magnesium conservation and serious clinical syndromes of magnesium deficiency.

Citations

Jan 1, 1997·Medical and Pediatric Oncology·G AricetaA Navajas
Jan 1, 1987·Journal of Neuro-oncology·S C Cohen, J E Mollman
Jan 1, 1986·Cancer Chemotherapy and Pharmacology·M P GorenM E Horowitz
Jan 1, 1982·Cancer Chemotherapy and Pharmacology·V M MacaulayE S Newlands
Jan 1, 1986·Cancer Chemotherapy and Pharmacology·S GrothM Rørth
Jan 1, 1994·Cancer Chemotherapy and Pharmacology·V PinzaniP Balmès
Jan 1, 1991·Cancer Chemotherapy and Pharmacology·R SkinnerA W Craft
Jan 1, 1989·Cancer Chemotherapy and Pharmacology·G Daugaard, U Abildgaard
Oct 1, 1988·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·S A Mendoza
Jan 1, 1991·Journal of Cancer Research and Clinical Oncology·M MarkmannW Hoskins
Dec 13, 1985·Pharmaceutisch Weekblad. Scientific Edition·D T SleijferN H Mulder
Nov 1, 1983·Indian Journal of Pediatrics·K JainB Clarkson
Mar 5, 2008·Cancer Chemotherapy and Pharmacology·Vincent Launay-VacherUNKNOWN European Society of Clinical Pharmacy Special Interest Group on Cancer Care
Jan 28, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rodney J HunterJudith A Smith
Jan 1, 1994·The American Journal of Medicine·R M McLean
Jul 1, 1985·Biological Psychiatry·T A Matzen, R L Martin
Apr 1, 1985·European Journal of Cancer & Clinical Oncology·G GiacconeA Calciati
Mar 1, 1989·Toxicology Letters·J P Fillastre, G Raguenez-Viotte
Jan 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·T R EvansJ L Mansi
Dec 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C C BergerH J Schmoll
Aug 10, 2006·Néphrologie & thérapeutique·Corinne Isnard-BagnisGilbert Deray
Jan 16, 1999·Pediatric Clinics of North America·M Grossi
Sep 6, 2000·Thrombosis Research·G I TognaL Caprino
Dec 13, 1980·Lancet·R A CoxI M Calder
Nov 17, 1984·Lancet·C B ThompsonE D Thomas
Jan 1, 1981·Annals of Emergency Medicine·T W GraberF J Baker
Sep 19, 2003·Seminars in Nephrology·Istvan Arany, Robert L Safirstein
Jan 1, 1984·Journal of the American College of Nutrition·J van Eys
Jan 1, 1986·Journal of the American College of Nutrition·E Laban, G A Charbon
Jun 30, 2010·Journal of the National Cancer Institute·Lois B TravisSophie D Fossa
Nov 9, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Annelies A van AngelenRené J M Bindels
Jul 27, 1985·British Medical Journal·F P CappuccioG A MacGregor
Jun 16, 1999·Clinical Chemistry and Laboratory Medicine : CCLM·M Crook
Mar 22, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·G T SandersR Sanders
Nov 10, 2011·Toxins·Ronald P MillerWilliam Brian Reeves
Feb 8, 2014·Japanese Journal of Clinical Oncology·Tatsuya YoshidaYuichiro Ohe
Nov 20, 2015·Expert Opinion on Pharmacotherapy·Giuseppe SantabarbaraCesare Gridelli
Jan 1, 1989·Medical Toxicology and Adverse Drug Experience·G Koren
Jan 1, 1988·The American Journal of the Medical Sciences·S UmekiR Soejima
Oct 1, 1989·The American Journal of the Medical Sciences·S UmekiR Soejima
Nov 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S M al-GhamdiR A Sutton
Nov 1, 1983·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·W M BennettI Singer
Sep 1, 1986·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Lam, D J Adelstein
Jul 1, 1986·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J A GordonA C Schoolwerth

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.