Hyponatremia and polyuria in children with central diabetes insipidus: challenges in diagnosis and management

The Journal of Pediatrics
R J FerryT Moshang

Abstract

Five patients with well-controlled, long-standing, central diabetes insipidus had acute development of dehydration, hyponatremia, and inappropriate natriuresis in the setting of polyuria resistant to exogenous antidiuretic hormone. Hyponatremia and dehydration worsened with fluid restriction or use of exogenous antidiuretic hormone. We discuss the challenges in diagnosis and management of probable salt wasting in children with central diabetes insipidus.

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Citations

Nov 16, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Miguel Angel De Los SantosMartha Rosario Calagua
Jan 13, 2009·Pediatric Neurology·Jainn-Jim LinHuei-Shyong Wang

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