Hypophosphatemia after live donor right hepatectomy

Surgery
Hae Won LeeKuhn Uk Lee

Abstract

It is known that hypophosphatemia can frequently develop after hepatectomy and may result from an increased renal phosphate leak. However, its clinical significance has not been well defined in live donor right hepatectomy (LDRH). The purpose of this study was to investigate the correlation between postoperative hypophosphatemia and both donor morbidity and the degree of hepatic resection in LDRH. In all, 88 live liver donors were enrolled, who had undergone right hemihepatectomy between January 2002 and December 2005. Based on the severity of the postoperative hypophosphatemia, we divided the donors into 3 groups: mild (1.5-2.5 mg/dL, n = 30), moderate (1.0-1.5 mg/dL, n = 41), and severe (<1.0 mg/dL, n = 17), and we compared the incidence of complications among these groups. In addition, we investigated the possible correlation between the nadir phosphorus levels and both remnant liver volume and alkaline phosphate (ALP) levels. All donors developed hypophosphatemia postoperatively. The mean value of the nadir phosphorus levels was 1.4 +/- 0.04 mg/dL. However, no significant difference was observed in the incidence of postoperative complications among the hypophosphatemia groups. The phosphorus level was positively correlated ...Continue Reading

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Citations

Sep 29, 2011·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Ding YuanKe-Fei Chen
May 17, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Malcolm H SquiresShishir K Maithel
Sep 3, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Joey SiuSaxon Connor
Jan 29, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Sang Hyun HongChul Soo Park
Sep 15, 2020·The American Surgeon·Paul WongLaleh Melstrom
Feb 11, 2016·Nihon yakurigaku zasshi. Folia pharmacologica Japonica·Sawako Tatsumi, Ken-Ichi Miyamoto
Apr 10, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Masaki HondaTaizo Hibi
Mar 4, 2014·Annals of Clinical Biochemistry·P ManghatR Swaminathan
Jul 24, 2021·Translational Research : the Journal of Laboratory and Clinical Medicine·Christoph ZechnerUNKNOWN Acute Liver Failure Study Group

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