Abstract
Hypophosphatemia in malnourished children during nutritional recovery (refeeding hypophosphatemia) is recognized as a cause of morbidity and mortality in adolescents with anorexia nervosa but has been only rarely reported to occur in younger children with other diagnoses. Over a 6-year period, we encountered three cases of refeeding hypophosphatemia in malnourished children admitted to a pediatric rehabilitation hospital. Two children had neurologic dysphagia and one had been starved by an abusive parent. The one patient who was symptomatic had obtundation, hemolytic anemia, rhabdomyolysis, and hepatocellular injury that began during refeeding and resolved with treatment. The signs and symptoms, pathophysiology, and treatment of refeeding hypophosphatemia are reviewed.
References
Dec 1, 1978·The Journal of Clinical Investigation·J P KnochelN W Carter
May 12, 1977·The New England Journal of Medicine·J H NewmanP Ziporin
Oct 27, 1977·The New England Journal of Medicine·L R O'ConnorJ E Bethune
Apr 1, 1992·Internal Medicine·S WadaN Nagata
Oct 21, 1991·The Medical Journal of Australia·P J Beumont, M Large
Jan 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·S M Solomon, D F Kirby
Nov 1, 1989·Archives of Surgery·M E Hayek, P G Eisenberg
Sep 1, 1989·American Journal of Diseases of Children·A G MezoffM K Farrell
Jan 1, 1988·Archives of Internal Medicine·J Halevy, S Bulvik
Nov 1, 1987·The American Journal of Clinical Nutrition·M J DibleyF L Trowbridge
Aug 15, 1985·The New England Journal of Medicine·M AubierR Pariente
Jun 20, 1974·The New England Journal of Medicine·P R CraddockH S Jacob
Aug 1, 1974·Archives of Internal Medicine·J C KlockW C Mentzer
Apr 1, 1971·Annals of Internal Medicine·M A LichtmanC Waterhouse
Sep 30, 1971·The New England Journal of Medicine·S F TravisF A Oski
Mar 1, 1983·Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine·P H Sheridan, M Collins
Mar 1, 1994·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·D E HallJ Snitzer
Mar 1, 1994·JPEN. Journal of Parenteral and Enteral Nutrition·T Maier-Dobersberger, H Lochs
Citations
Sep 5, 2002·The International Journal of Eating Disorders·Katrin ImbierowiczReinhard Liedtke
Jul 13, 2001·The International Journal of Eating Disorders·G AlexandridisM Elisaf
Feb 5, 2004·Journal of the American College of Surgeons·Beth E TaylorCraig M Coopersmith
Jan 1, 2003·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Rollyn M OrnsteinI Ronald Shenker
Dec 6, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Juliana Fernandez Santana e MenesesEmílio Lopes
Feb 1, 2006·Archives of Disease in Childhood·P B SullivanA G Thomas
May 17, 2011·Gut·Jia V LiElaine Holmes
Apr 26, 2001·Postgraduate Medical Journal·L Håglin
Aug 26, 2014·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·UNKNOWN Society for Adolescent Health and Medicine
Feb 4, 2010·Nutrition·Akwasi Afriyie BoatengMartin Crook
Jun 4, 2008·The International Journal of Eating Disorders·Alice Walder, Pierre Baumann
Jul 10, 2016·Indian Journal of Pediatrics·Satish Kumar ShahRakesh Lodha
Oct 7, 2016·Bulletin of the World Health Organization·Kirkby D Tickell, Donna M Denno
Nov 16, 2004·Revista do Hospital das Clínicas·Fernanda Souza de MenezesWerther Brunow de Carvalho
Jul 21, 2006·Journal of Intensive Care Medicine·Fernanda Souza de MenezesWerther Brunow de Carvalho
Dec 7, 2007·Clinical Pediatrics·Andrea BalazsLefkothea P Karaviti
Sep 17, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·J J CottrellD G Burrin
Oct 7, 2006·Current Opinion in Gastroenterology·D H Alpers, S Klein
Dec 17, 2009·Food and Nutrition Bulletin·Michael H Golden
Nov 26, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Matthew C Byrnes, Jessica Stangenes
Feb 5, 2000·Neurologic Clinics·W S David