Hypophysectomy exerts a radioprotective effect on frog lens

Experientia
J H HaydenG R Merriam

Abstract

Exposure to X-rays usually causes cataracts in frogs. These cataracts are always preceded by misalignment of the structures called meridional rows (MR). When cell division is completely halted by hypophysectomy, however, irradiation no longer disturbs the orientation of the MR. Since the MR are the structures formed as lens epithelial cells differentiate into lens fibres it is reasonable to propose that radiocataractogenesis depends upon a mitosis-driven formation of pathological fibres from epithelial cells that have been rendered abnormal by exposure to X-rays.

References

Sep 1, 1978·Archives of Ophthalmology·B W Streeten, J Eshaghian
Jun 1, 1976·Archives of Ophthalmology·B V WorgulD Srinivasan
Jan 1, 1975·General and Comparative Endocrinology·R Van BuskirkN Wainwright
Aug 15, 1975·Experientia·H RothsteinB V Worgul

❮ Previous
Next ❯

Citations

May 16, 2014·Journal of Radiation Research·Nobuyuki HamadaHitoshi Sato
Mar 1, 1989·Experimental Eye Research·D S HolsclawB V Worgul
Nov 23, 2013·Radiation Research·Joseph R Dynlacht
Jan 26, 2010·Radiation Research·Mark A HendersonJoseph R Dynlacht
Nov 26, 2016·Radiation Protection Dosimetry·E Forssell-Aronsson, R A Quinlan
Jun 1, 1984·Experimental Eye Research·O Gona
Dec 3, 2016·International Journal of Radiation Biology·Nobuyuki Hamada
Jan 1, 1986·Zeitschrift Für Parasitenkunde·D A VuittonJ A Grimaud

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.