Hypopituitarism after traumatic brain injury

Endocrinology and Metabolism Clinics of North America
Eva Fernandez-RodriguezF F Casanueva

Abstract

The prevalence of hypopituitarism after traumatic brain (TBI) injury is widely variable in the literature; a meta-analysis determined a pooled prevalence of anterior hypopituitarism of 27.5%. Growth hormone deficiency is the most prevalent hormone insufficiency after TBI; however, the prevalence of each type of pituitary deficiency is influenced by the assays used for diagnosis, severity of head trauma, and time of evaluation. Recent studies have demonstrated improvement in cognitive function and cognitive quality of life with substitution therapy in GH-deficient patients after TBI.

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Citations

Aug 5, 2015·Journal of Clinical Medicine·Robert A Scranton, David S Baskin
Aug 5, 2015·Journal of Clinical Medicine·Christine Streetz-van der WerfIlonka Kreitschmann-Andermahr
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Apr 28, 2018·Brain Injury : [BI]·Racine Marcus BrownRisa Nakase-Richardson
Feb 11, 2020·Frontiers in Neurology·J Bryce OrtizJonathan Lifshitz
Jul 20, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Eileen FanJean-Pierre Chanoine

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