PMID: 11926206Apr 3, 2002Paper

Hypopituitarism, deficiency of factors V and VIII and von Willebrand factor: an uncommon association

Journal of Pediatric Endocrinology & Metabolism : JPEM
Nuvarte SetianElbio A D'Amico

Abstract

A 9 year-old boy with hypopituitarism and blood coagulation abnormalities is presented and discussed. The association between acquired von Willebrand disease and hypothyroidism has been reported but the combination of hypopituitarism and coagulopathy is unusual. Combined multiple clotting deficiencies are rare and, when present, factors V and VIII is the commonest association. Although it is known that hypothyroid patients may have a decrease in von Willebrand's factor (vWf) and factor VIII, there are no reports of hypopituitarism associated with combined deficiency of factors V, VIII, and vWf.

References

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Citations

May 20, 2015·European Journal of Endocrinology·Andrea M IsidoriAshley B Grossman
Jun 14, 2008·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Miriam C OliveiraJúlia F S Pereira-Lima
Sep 1, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Claire FlotThomas Edouard
May 1, 2021·Journal of the Endocrine Society·Stefan FischliChristoph Henzen

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