Jan 1, 1989

Hypoplastic left heart syndrome: lack of correlation between preoperative demographic and laboratory findings and survival following palliative surgery

Pediatric Cardiology
G BarberW I Norwood

Abstract

To determine whether preoperative demographic and metabolic variables correlated with early or late survival following palliative surgery for hypoplastic left heart syndrome, we reviewed the charts of 89 patients operated upon from October 1984 to January 1987. The variables analyzed were age at operation, lowest preoperative pH and H2CO3, highest preoperative arterial oxygen saturation, the occurrence of a preoperative cardiorespiratory arrest, and location of birth relative to the surgical institution. The data were evaluated by chi-squared, multivariate, and life-table analyses to the end of the first postoperative year. None of the factors analyzed significantly correlated with either short-term (less than or equal to 30 days) or long-term (greater than 30 days) survival. Thus, neither demographic nor metabolic factors including prior cardiorespiratory arrest should be considered contraindications to surgical palliation for hypoplastic left heart syndrome.

  • References6
  • Citations5

Mentioned in this Paper

Metabolic Process, Cellular
Arterial Oxygen Saturation Measurement
Dioxygen
Carbonic Acid Ions
Congenital Heart Defects
Arterial Oxygen Saturation (Observable Entity)
Hypoplastic Left Heart Syndrome
Age Factors
Postoperative Period
Immunodeficiency Syndrome, Variable

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.