Hypoplastic left heart syndrome
The evolution of the present approach to the newborn with hypoplastic left heart is outlined. Preoperatively, maintenance of ductal patency with prostaglandin E1 and balancing of systemic and pulmonary blood flow are essential. Operative details of the first-stage palliation and the definitive second-stage procedure are described. The more recent adoption of an intermediate-stage hemi-Fontan procedure is also described. Since January 1989, 151 patients have been treated using this three-stage approach, with 109 early survivors. Seventy-eight have undergone the hemi-Fontan operation with nine deaths (5 of whom came to this stage early nonelectively because of shunt failure or ventricular dysfunction). Twenty-seven of the 78 patients undergoing hemi-Fontan operation have subsequently undergone definitive Fontan procedures with no deaths.
Catheter interventional treatment of Sano shunt obstruction in patients following modified Norwood palliation for hypoplastic left heart syndrome
Anomalous subaortic left brachiocephalic vein associated with tricuspid atresia: a successful bidirectional cavopulmonary connection
Survival in neonatal biventricular repair of left-sided cardiac obstructive lesions associated with hypoplastic left ventricle
Calculating blood flow from Doppler measurements in the systemic-to-pulmonary artery shunt after the Norwood operation: a method based on computational fluid dynamics
Morphometric analysis of unbalanced common atrioventricular canal using two-dimensional echocardiography
An institutional experience with second- and third-stage palliative procedures for hypoplastic left heart syndrome: the impact of the bidirectional cavopulmonary shunt
The hypoplastic left heart syndrome with intact atrial septum: atrial morphology, pulmonary vascular histopathology and outcome
Hypoplastic left heart syndrome with intact atrial septum associated with deletion of the short arm of chromosome 18
A comparison of hospital costs with reimbursement received for patients undergoing the Norwood procedure for hypoplasia of the left heart
Application of fresh and cryopreserved homografts harvested from transplant patients for correction of complex congenital heart disease
Developments in interventional catheterisation and progress in surgery for congenital heart disease: achieving a balance
Developments in interventional cardiac catheterisation and progress in surgery for congenital heart disease: achieving a balance
Surgery for infants with a hypoplastic systemic ventricle and severe outflow obstruction: early results with a modified Norwood procedure
Changes in cerebral oxygen saturation and blood flow during hypoxic gas ventilation therapy in HLHS and CoA/IAA complex with markedly increased pulmonary blood flow
Fate of infants with hypoplastic left heart syndrome listed for cardiac transplantation: a multicenter study
Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage I mortality
Heart transplantation in children: indications. Report of the Ad Hoc Subcommittee of the Pediatric Committee of the American Society of Transplantation (AST)
Oxygenation in patients with a functionally univentricular circulation and complete mixing of blood: are saturation and flow interchangeable?
Consensus on timing of intervention for common congenital heart diseases: part II - cyanotic heart defects
Left heart obstructive lesions and left ventricular growth in the midtrimester fetus. A longitudinal study
Unrecognized pulmonary venous desaturation early after Norwood palliation confounds Gp:Gs assessment and compromises oxygen delivery
Bidirectional Glenn procedure improves the mechanical efficiency of a total cavopulmonary connection in high-risk fontan candidates
Implementing the Sano modification in an experimental model of first-stage palliation of hypoplastic left heart syndrome
Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: The European Association for Cardio-Thoracic Surgery (EACTS) and the Association for European Paediatric and Congenital Cardiology (AEPC) Hypoplastic Left Heart Syndrome Guidelines Task Force.
Perioperative care of an infant with an anomalous left innominate artery arising from the main pulmonary artery
Right-ventricular global longitudinal strain may predict neo-aortic arch obstruction after Norwood/Sano procedure in children with hypoplastic left heart syndrome
Effects of protocol-based management on the post-operative outcome after systemic to pulmonary shunt
Analytical identification of ideal pulmonary-systemic flow balance in patients with bidirectional cavopulmonary shunt and univentricular circulation: oxygen delivery or tissue oxygenation?
Ventriculoarterial coupling in palliated hypoplastic left heart syndrome: Noninvasive assessment of the effects of surgical arch reconstruction and shunt type
Blood And Marrow Transplantation
The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.