Hypoplastic left heart syndrome

Lancet
David BarronWilliam Brawn

Abstract

Hypoplastic left heart syndrome is a rare congenital heart defect in which the left side of the heart is underdeveloped. Surgical management of hypoplastic left heart syndrome has changed the prognosis of the condition that was previously regarded as fatal. We discuss surgical strategies based on staged procedures, with the right ventricle supporting both systemic and pulmonary circulation. We also discuss other management options, such as neonatal transplantation and the recent innovation of hybrid techniques. Surgical techniques and the understanding of the pathophysiology of this condition have been at the forefront of neonatal cardiac surgery and intensive care. The management of the syndrome remains a challenge because affected children grow into adolescence and adulthood posing various new problems and demands.

References

May 1, 1971·Thorax·F Fontan, E Baudet
Jan 6, 1983·The New England Journal of Medicine·W I NorwoodD D Hansen
Nov 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·M Abu-HarbC Wren
Jul 1, 1994·Archives of Disease in Childhood·M Abu-HarbC Wren
Oct 7, 1997·Lancet·F L RaymondC M Ogilvie Mackie
Jan 22, 1998·The Annals of Thoracic Surgery·U BartramR Van Praagh
Jan 29, 2000·The Journal of Thoracic and Cardiovascular Surgery·S H DaebritzR A Jonas
May 8, 2000·The Annals of Thoracic Surgery·C I TchervenkovS A Tahta
Aug 5, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·E MalecJ Pajak
Mar 15, 2001·The New England Journal of Medicine·L J WestJ G Coles
Jul 10, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J William GaynorThomas L Spray
Aug 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·S RichmondM Abu Harb
May 20, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Edward MalecTomasz Mroczek
Aug 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Shunji SanoShin-ichi Ohtsuki
Nov 11, 2003·Journal of the American College of Cardiology·Doff B McElhinneyElizabeth Goldmuntz
Dec 11, 2003·The Journal of Thoracic and Cardiovascular Surgery·N S GhanayemJ S Tweddell
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·George M HoffmanStuart Berger
Oct 30, 2004·The Annals of Thoracic Surgery·Jeffrey P JacobsGeorge R Daicoff
Nov 25, 2004·The Annals of Thoracic Surgery·Yoshihisa TanoueShiro Ishikawa
May 18, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M R K ChrisantUNKNOWN Pediatric Heart Transplant Study Group
Jun 25, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A AtzeiK H Nicolaides
Jan 10, 2006·The Journal of Thoracic and Cardiovascular Surgery·Emile A BachaZiyad M Hijazi
Jun 24, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S V RasiahJ Zamora
May 24, 2008·The Annals of Thoracic Surgery·Jenifer A GlatzJames S Tweddell
Jul 8, 2008·The Journal of Thoracic and Cardiovascular Surgery·David A HehirSarah Tabbutt

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Citations

Nov 26, 2010·Der Radiologe·R D Dalla PozzaH Netz
Jan 30, 2014·The Journal of Thoracic and Cardiovascular Surgery·Noritaka OtaKisaburo Sakamoto
Jun 14, 2013·Seminars in Fetal & Neonatal Medicine·Dietmar Schranz, Ina Michel-Behnke
Jul 11, 2012·Nature Reviews. Gastroenterology & Hepatology·Babette PeetersRaoul C M Hennekam
Feb 1, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Walter KnirschBeatrice Latal
Dec 14, 2011·European Heart Journal Cardiovascular Imaging·Hannah R Bellsham-RevellJohn M Simpson
Dec 4, 2010·Experimental Biology and Medicine·Kenneth R Knecht, Charles W Leffler
Feb 8, 2013·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Tapas K MondalJan W Jansen
Jan 24, 2013·Medical & Biological Engineering & Computing·A de VecchiN P Smith
Jan 15, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Hitendu DaveOliver Kretschmar
Nov 16, 2013·Cardiology in the Young·J Bryan CarmodyJennifer R Charlton
May 2, 2012·Nursing Research and Practice·Gwen R RempelJoyce Magill-Evans
Aug 2, 2014·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Allison K BlackBradley B Keller
Jan 16, 2016·Cardiology in the Young·Tina TrachselAnna Cavigelli-Brunner
Jan 14, 2016·Pediatric Cardiology·Sjoerd S M BossersWillem A Helbing
Sep 24, 2011·Legal Medicine·Yoshie HayashizakiMasato Funayama
Jul 15, 2015·Cardiology in the Young·Charles R Cole, Pirooz Eghtesady
Jul 19, 2015·European Heart Journal Cardiovascular Imaging·Kuberan PushparajahReza Razavi
Jun 20, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Christel Eckmann-ScholzIbrahim Alkatout
Aug 11, 2011·Korean journal of pediatrics·Sin Weon Yun
Jul 21, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Nikita M PatelRavi K Birla
Jan 1, 2013·Journal of the American College of Cardiology·Hannah R Bellsham-RevellReza Razavi
Jan 4, 2012·Journal of the American College of Cardiology·Edward J HickeyBrian W McCrindle
Nov 18, 2015·Journal of Pediatric Surgery·Brian T CraigDai H Chung
Sep 24, 2016·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Heidi MäenpääAnne Sarajuuri
Dec 23, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·R EllingJ Grohmann
May 26, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J RychikM P Johnson
Dec 21, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Dietmar SchranzHakan Akintuerk
Jun 28, 2011·Journal for Specialists in Pediatric Nursing : JSPN·Anra Lee, Gwen R Rempel
May 4, 2011·Journal of Paediatrics and Child Health·David S WinlawGary F Sholler
Jun 10, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jan Hinnerk HansenHans-Heiner Kramer
Apr 1, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Bari MurtuzaWilliam J Brawn

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