Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study

Journal of Anesthesia
Ondrej JorVladimir Cerny

Abstract

Hypotension after induction of general anesthesia (GAIH) is common in anesthesiology practice and can impact outcomes. In this prospective multicenter, cross-sectional, observational study, the hypotension was defined as a decrease in mean arterial pressure of > 30% compared to the first measurement in the operation theatre before general anesthesia (GA) induction. Blood pressure was measured immediately at the time of endotracheal intubation (TETI), at five (T5) and 10 (T10) minutes after. All subjects aged > 18 years undergoing elective non-cardiac surgery under GA were included. The goals were description of GAIH occurrence, the association of GAIH with selected comorbidities, chronic medications, and anesthetics with GAIH, and the type and efficacy of interventions used to correct hypotension. Data from 661 subjects, whose GA was induced with propofol and sufentanil, were analyzed. In 36.5% of subjects, GAIH was observed at ≥ 1 of the assessed time points. GAIH was present in 2.9% subjects at all time points. The probability of GAIH is raising with age, degree of hypertension at time of arrival to theatre and presence of diabetes. The type of volatile anesthetic was not associated with the occurrence of GAIH. The overall ef...Continue Reading

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References

Jul 25, 2003·British Journal of Anaesthesia·R W D Nickalls, W W Mapleson
Aug 24, 2005·Anesthesia and Analgesia·David L ReichCarol A Bodian
May 8, 2014·Journal of Anaesthesiology, Clinical Pharmacology·Mansoor MasjediAli Hoseinipour

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Citations

Sep 5, 2020·Journal of Anesthesia·Naoyuki Hirata, Michiaki Yamakage
Sep 26, 2019·Journal of Anesthesia·Bailong HuXiaohua Zou
Jul 30, 2020·General Thoracic and Cardiovascular Surgery·Satoru DomotoHiroshi Niinami
May 27, 2021·Case Reports in Anesthesiology·Tomoe SatohMichiaki Yamakage

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