Abstract
Transient hypotension may be one of many factors contributing to the high prevalence of falls among elderly people. To determine the frequency and magnitude of hypotensive responses to common daily activities, and their potential relationship to falls in the elderly, we examined blood pressure (BP) and heart rate during a standardized series of activities in 38 institutionalized recurrent fallers (age, 87 +/- 6 years), 20 institutionalized nonfallers (age, 85 +/- 5 years), and 10 healthy young control subjects (age, 24 +/- 3 years). The coefficient of variation for systolic BP during all activities was higher in elderly subjects (fallers, 14% +/- 5%; nonfallers, 12% +/- 3%) than in young control subjects (8% +/- 1%). In contrast, the coefficient of variation for heart rate during all activities was higher in young subjects than in the elderly subjects. Elderly subjects had marked BP reduction following meals and nitroglycerin, which was significantly greater in fallers than in nonfallers, independent of the cause of the fall. Thus, institutionalized elderly have marked BP variability and hypotensive responses to meals and nitroglycerin. A decline in BP during common preload-reducing stresses may predispose some elderly people t...Continue Reading
Citations
May 1, 1992·Journal of General Internal Medicine·P Starer, L S Libow
Jul 9, 2013·Current Hypertension Reports·Amy C Arnold, Cyndya Shibao
Aug 31, 2013·Aging Clinical and Experimental Research·Marte Rognstad MellingsæterAnette Hylen Ranhoff
Jan 1, 1996·Archives of Gerontology and Geriatrics·G SalvioliJ M Pradelli
Jul 1, 2004·Preventive Medicine·Erik Roj LarsenAnders Foldspang
Jul 14, 2001·Journal of the American College of Cardiology·K KarioS Wassertheil-Smoller
May 20, 1998·British Journal of Urology·D S Coffey
Aug 15, 1996·Annals of the New York Academy of Sciences·T Rosenthal
Mar 19, 2014·Journal of the American Medical Directors Association·Laurence G TrahairKaren L Jones
Oct 12, 2014·Current Cardiology Reports·Italo Biaggioni
Feb 13, 2016·Scientific Reports·Zhanfang SunBeisha Tang
Jun 1, 2013·Journal of the American Society of Hypertension : JASH·Cyndya ShibaoUNKNOWN American Society of Hypertension Writing Group
Feb 14, 1998·Journal of Gerontological Nursing·M D Lilley
Mar 6, 2013·The Journal of Clinical Hypertension·Cyndya ShibaoItalo Biaggioni
Nov 29, 2012·Geriatrics & Gerontology International·Frederic BlochGilles Kemoun
Jan 15, 1992·The American Journal of Cardiology·S M RyanL A Lipsitz
Jun 23, 2015·Archivos de cardiología de México·Enrique AsensioDaniela Juárez
Aug 16, 2002·Clinics in Geriatric Medicine·Laurence Z Rubenstein, Karen R Josephson
Dec 1, 1991·Journal of the American Geriatrics Society·J E Morley
Jan 1, 1994·Journal of the American Geriatrics Society·N B Alexander
Sep 1, 1994·Journal of the American Geriatrics Society·W S Aronow, C Ahn
Sep 1, 1997·Journal of the American Geriatrics Society·W S Aronow, C Ahn
Oct 13, 2014·Journal of the American Medical Directors Association·Shailaja NairDiana Gentilcore
Oct 16, 2010·Journal of Aging and Health·Frédéric BlochGilles Kemoun
Oct 1, 1996·Clinical Pharmacology and Therapeutics·L A LipsitzC Waksmonski
Apr 1, 1992·Journal of Clinical Pharmacy and Therapeutics·V F TrewinG B Veitch
Mar 1, 1996·American Journal of Physical Medicine & Rehabilitation·K M MeansP S O'Sullivan