PMID: 2484870Aug 1, 1989Paper

Hypothyroidism with spontaneous progression to hyperthyroidism

Thyroidology
A L Barkan

Abstract

Chronic lymphocytic thyroiditis (Hashimoto's disease) is usually regarded as a stable and irreversible condition. This report describes a patient with autoimmune hypothyroidism who subsequently developed hyperthyroid Graves' disease. Patients with Hashimoto's thyroiditis should be followed regularly, and the development of clinical and/or biochemical hyperthyroidism should alert the physician to the possibility of another thyroid disease.

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