Hypoxia due to intrapulmonary vascular dilatation in a toddler with a congenital portacaval shunt: case report

BMC Pulmonary Medicine
Mohammed T AlsamriAbdul-Kader Souid

Abstract

The term hepatopulmonary syndrome typically applies to cyanosis that results from "intrapulmonary vascular dilatation" due to advanced liver disease. Similar findings may result from a congenital portosystemic shunt without liver disease. An adverse consequence of such shunts is intrapulmonary vascular dilatation, which affects the microvascular gas exchange units for oxygen. Here, we describe a toddler with chronic cyanosis, exercise intolerance, and finger clubbing due to a malformation shunt between the portal vein and the inferior vena cava. A transcatheter embolization of the shunt resulted in resolution of his findings. Congenital portosystemic shunts need to be considered in the differential diagnosis of cyanosis.

References

Apr 1, 1978·Chest·H H DavisB A Schainker
Mar 1, 1996·Clinics in Chest Medicine·D E Schraufnagel, J M Kay
Aug 4, 1999·The Journal of Pediatrics·T UchinoF Endo
Sep 7, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Federico P GómezRobert Rodríguez-Roisin
Nov 2, 2004·The European Respiratory Journal·R Rodríguez-RoisinUNKNOWN ERS Task Force Pulmonary-Hepatic Vascular Disorders (PHD) Scientific Committee
Feb 4, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Timothy D Woods, Ashvin Patel
May 17, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Eduardo Alonso-GamarraManuel López-Santamaría
Feb 12, 2013·Seminars in Liver Disease·O BernardE Jacquemin
Mar 31, 2018·World Journal of Gastroenterology : WJG·Stergios SoulaidopoulosIoannis Goulis

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