Hysteroscopy as a valid tool for endometrial pathology in patients with postmenopausal bleeding or asymptomatic patients with a thickened endometrium: hysteroscopic and histological results

Gynecologic and Obstetric Investigation
Rosalia Maria Rita LoiaconoVito Trojano

Abstract

This study compares hysteroscopic and histopathological results in postmenopausal women with abnormal uterine bleeding (AUB) and asymptomatic postmenopausal women with a thickened endometrium. This is a retrospective study of 570 cases hysteroscopically examined between January 2008 and July 2012. The patients were followed up at the Istituto Tumori 'Giovanni Paolo II', Bari, Italy. A total of 320 of the 570 cases were selected. The inclusion criteria were transvaginal ultrasound, hysteroscopy and endometrial biopsy. In the AUB group, if the hysteroscopy results were normal, a sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 100, 95, 71 and 100%, respectively, were achieved, while in the asymptomatic group these values were 100, 97, 90 and 100%, respectively. For both the group with polyps and that with myomas, the sensitivity, specificity, PPV and NPV were 100%. For endometrial hyperplasia, hysteroscopy showed a sensitivity, specificity, PPV and NPV of 81, 96, 87 and 93%, respectively, in the AUB group, while in the asymptomatic group, the sensitivity was 60%, the specificity and PPV were 100%, and the NPV was 98%. The sensitivity of hysteroscopy for endometrial cancer was 63%, t...Continue Reading

Citations

Mar 5, 2016·Journal of Minimally Invasive Gynecology·Manuel Maria IanieriMarcello Ceccaroni
Apr 6, 2017·Journal of Korean Medical Science·Min Kyoung KimSeok Kyo Seo
Sep 18, 2016·Women's Health·Daniel Spadoto-DiasRogério Dias
Mar 16, 2018·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Cristina RemondiEmilio Piccione
May 12, 2018·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Josephine K T DermawanFadi W Abdul-Karim
May 13, 2020·Climacteric : the Journal of the International Menopause Society·R FagioliA Di Spiezio Sardo
Dec 31, 2019·BioMed Research International·Hui-Yu HuangChin-Jung Wang
Sep 27, 2018·Gynecology and Minimally Invasive Therapy·Deeksha PandeyHsuan Su
Jul 1, 2017·Gynecology and Minimally Invasive Therapy·Ci HuangDah-Ching Ding

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