Ibuprofen timing for hand surgery in ambulatory care

Acta ortopedica brasileira
Enrico GiulianiAlberto Barbieri

Abstract

To evaluate the effect of pre-operative administration of ibuprofen on post-operative pain control vs. early post-operative administration for hand surgery procedures performed under local anaesthesia in ambulatory care. Candidates to trigger finger release by De Quervain tenosynovitis and carpal tunnel operation under local anesthesia were enrolled in the study. Group A received 400 mg ibuprofen before the operation and placebo after the procedure; group B received placebo before the operation and ibuprofen 400 mg at the end of the procedure; both groups received ibuprofen 400 mg every 6h thereafter. Visual analogue scale (VAS) was measured at fixed times before and every 6h after surgery, for a total follow-up of 18h. Groups were similar according to age, gender and type of surgery. Median VAS values did not produce any statistical significance, while there was a statistically significant difference on pre-operative and early post-operative VAS values between groups (A -8.53 mm vs. B 3.36 mm, p=0.0085). Average pain levels were well controlled by local anesthesia and post-operative ibuprofen analgesia. Pre-operative ibuprofen administration can contribute to improve early pain management. Level of Evidence II, Therapeutic Stu...Continue Reading

References

Sep 16, 2000·The Journal of Bone and Joint Surgery. British Volume·J CastellanosC Bertrán
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Dec 6, 2005·Regional Anesthesia and Pain Medicine·Philippe MacaireXavier Capdevila
Jan 31, 2006·The Journal of Hand Surgery·Mark Ryzewicz, Jennifer Moriatis Wolf
Dec 8, 2007·The Journal of the American Academy of Orthopaedic Surgeons·Asif M IlyasJoseph Thoder
Dec 5, 2009·The Journal of Hand Surgery, European Volume·Andrew YamFok-Chuan Yong
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Jun 15, 2011·Best Practice & Research. Clinical Rheumatology·Keith T Palmer
Jun 15, 2011·Best Practice & Research. Clinical Rheumatology·José-Luis AndréuJesús Sanz

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Citations

May 15, 2018·The Laryngoscope·Alexander MichaelGlenn Isaacson
Mar 3, 2020·Clinics in Plastic Surgery·Evyn L NeumeisterYoussef El Bitar
Apr 14, 2021·The Cochrane Database of Systematic Reviews·Mabel Qi He LeowEdwin Sy Chan
Jun 15, 2021·The Cochrane Database of Systematic Reviews·Brett DolemanJohn P Williams

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