Ibuprofen versus placebo in the relief of post-episiotomy pain

Current Medical Research and Opinion
E Taina

Abstract

Thirty post-partum patients, aged 19 to 37 years, were treated for episiotomy pain and inflammation with either 1600 mg ibuprofen (400 mg every 6 hours) or placebo daily for 7 days in a completely randomized, double-blind study. Pain intensity, movement restriction and extent of swelling in the episiotomy were recorded prior to treatment and at intervals of 1, 3, 5 and 7 days. The difference scores of pain intensity, movement restriction and extent of swelling were calculated from the differences between pretreatment and post-treatment values. By all methods of evaluation, ibuprofen was significantly more effective than placebo at 1 and 3 days after the initiation of the treatment. Only 2 minor side-effects were recorded, both in the placebo group.

References

Jan 1, 1972·Current Medical Research and Opinion·R F van Wering, O P Bleker
Jun 1, 1974·Clinical Pharmacology and Therapeutics·S S BloomfieldJ Mitchell
Nov 1, 1965·The American Journal of the Medical Sciences·W T Beaver

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Citations

Dec 7, 2002·Obstetrics and Gynecology·Vatche A MinassianKeeli Stumbo
Feb 1, 1990·Journal of Clinical Pharmacy and Therapeutics·M J KendallR Rau
Jan 1, 1987·Current Medical Research and Opinion·R F HarrisonE A Wickham
Jul 13, 1984·The American Journal of Medicine·V Slavic-SvircevB F Rusy
Jun 1, 1989·Journal of Clinical Pharmacology·B P SchachtelR I Baybutt
Feb 27, 2013·The Cochrane Database of Systematic Reviews·Doris ChouA Metin Gülmezoglu
Jul 15, 2016·The Cochrane Database of Systematic Reviews·Francesca WuytackBrian J Cleary
Nov 1, 1985·British Journal of Obstetrics and Gynaecology·B N WaltersT A Mustill
Feb 11, 1984·British Medical Journal·C FeinmannR Cawley
Jan 12, 2021·The Cochrane Database of Systematic Reviews·Francesca WuytackBrian J Cleary

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